Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.42 |
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.42 |
| ▸ | HTT | P42858 | 5/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 5/20 | 0.40 |
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | RECQL | P46063 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.34 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL917448 | 1.00 | ALDH1A1 (0.42) | ALDH1A1KDM4EMAPTMAPK1HTT | |
| SCHEMBL17546730 | 0.87 | HSPA5 (0.46) | ALDH1A1KDM4EMAPTMAPK1HTT | |
| SCHEMBL12563169 | 0.81 | L3MBTL1 (0.37) | ALDH1A1KDM4EMAPTGAAL3MBTL1 | |
| SCHEMBL919097 | 0.80 | ALDH1A1 (0.48) | ALDH1A1KDM4EMAPTMAPK1HTT | |
| SCHEMBL919098 | 0.80 | ALDH1A1 (0.48) | ALDH1A1KDM4EMAPTMAPK1HTT | |
| SCHEMBL12904890 | 0.80 | ALDH1A1 (0.48) | ALDH1A1KDM4EMAPTMAPK1HTT | |
| Acetic Acid SCHEMBL1230109 | 0.80 | HSPA5 (0.39) | ALDH1A1KDM4EMAPTMAPK1HTT | |
| SCHEMBL19050607 | 0.79 | L3MBTL1 (0.37) | ALDH1A1KDM4EMAPTMAPK1HTT | |
| SCHEMBL12563171 | 0.78 | L3MBTL1 (0.36) | ALDH1A1KDM4EMAPTMAPK1HTT | |
| SCHEMBL918599 | 0.78 | L3MBTL1 (0.50) | ALDH1A1KDM4EMAPTMAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9273024-B2 | Synthesis of cyclic carbonates | UNIVERSITY OF YORK (GB) | 2016-03-01 | — | — | US | disclosed |
| US-9273024-B2 | Synthesis of cyclic carbonates | UNIVERSITY OF YORK (GB) | 2016-03-01 | — | — | US | disclosed |
| US-9242955-B2 | Synthesis of cyclic carbonates | UNIVERSITY OF YORK (GB) | 2016-01-26 | — | — | US | disclosed |
| US-9242955-B2 | Synthesis of cyclic carbonates | UNIVERSITY OF YORK (GB) | 2016-01-26 | — | — | US | disclosed |
| EP-2257559-B1 | SYNTHESIS OF CYCLIC CARBONATES | UNIV YORK (GB) | 2014-10-15 | — | — | EP | disclosed |
| US-20130317237-A1 | SYNTEHSIS OF CYCLIC CARBONATES | UNIVERSITY OF NEW CASTLE UPON TYNE (GB) | 2013-11-28 | — | — | US | disclosed |
| EP-2146977-B1 | SYNTHESIS OF CYCLIC CARBONATES IN THE PRESENCE OF DIMERIC ALUMINIUM (SALEN) CATALYSTS | UNIV NEWCASTLE (GB) | 2012-11-14 | — | — | EP | disclosed |
| US-20110015409-A1 | SYNTHESIS OF CYCLIC CARBONATES | UNIVERSITY OF NEWCASTLE UPON TYNE (GB) | 2011-01-20 | — | — | US | disclosed |
| US-20110015409-A1 | SYNTHESIS OF CYCLIC CARBONATES | UNIVERSITY OF NEWCASTLE UPON TYNE (GB) | 2011-01-20 | — | — | US | disclosed |
| US-20100130752-A1 | SYNTHESIS OF CYCLIC CARBONATES | UNIVERSITY OF NEWCASTLE UPON TYNE (GB) | 2010-05-27 | — | — | US | disclosed |
| US-20100130752-A1 | SYNTHESIS OF CYCLIC CARBONATES | UNIVERSITY OF NEWCASTLE UPON TYNE (GB) | 2010-05-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100130752-A1 | SYNTHESIS OF CYCLIC CARBONATES | CA2, SCO2, CA7 | ALDH1A1 3403/4885KDM4E 906/4885MAPT 2806/4885 |
| US-20130317237-A1 | SYNTEHSIS OF CYCLIC CARBONATES | CA12, SUCLA2, LMNA | ALDH1A1 3080/4885KDM4E 3848/4885MAPT 4780/4885 |
| US-20110015409-A1 | SYNTHESIS OF CYCLIC CARBONATES | NR3C2, NR2C2, NR3C1 | ALDH1A1 3200/4885KDM4E 3807/4885MAPT 4670/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.