Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.39 |
| ▸ | GBA1 | P04062 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HGFAC | Q04756 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.34 |
| ▸ | MLNR | O43193 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | C1R | P00736 | 1/20 | 0.34 |
| ▸ | F10 | P00742 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL91751 | 0.86 | KMT2A (0.35) | KMT2AGBA1MAPTMEN1TDP1 | |
| SCHEMBL91725 | 0.86 | NR1H4 (0.35) | KMT2AGBA1MAPTMEN1TDP1 | |
| SCHEMBL91791 | 0.81 | KIF11 (0.35) | MAPTTDP1ESR1ALDH1A1POLB | |
| SCHEMBL91733 | 0.80 | ESR1 (0.37) | MAPTESR1ALDH1A1LMNAGAA | |
| SCHEMBL91877 | 0.79 | PTGDR2 (0.32) | PTGDR2 | |
| SCHEMBL91720 | 0.79 | KMT2A (0.39) | KMT2AGBA1MAPTMEN1TDP1 | |
| SCHEMBL91745 | 0.77 | KMT2A (0.37) | KMT2AGBA1MAPTMEN1TDP1 | |
| SCHEMBL91782 | 0.75 | KMT2A (0.41) | KMT2AGBA1MAPTMEN1TDP1 | |
| SCHEMBL91839 | 0.71 | FFAR4 (0.33) | ESR1 | |
| SCHEMBL91709 | 0.70 | LMNA (0.38) | KMT2AMAPTMEN1TDP1ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8129002-B2 | Compounds for use in liquid crystal media | MERCK PATENT GMBH (DE) | 2012-03-06 | — | — | US | disclosed |