SCHEMBL917818

SCHEMBL917818

COC(=O)c1cc(OC)c(C(C)C)c(OC)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.50
KDM4E B2RXH2 4/20 0.48
ALDH1A1 P00352 2/20 0.48
CA1 P00915 2/20 0.48
CA2 P00918 2/20 0.48
CA12 O43570 1/20 0.48
CA7 P43166 1/20 0.48
CA9 Q16790 1/20 0.48
CA14 Q9ULX7 1/20 0.48
CNR2 P34972 1/20 0.47
GAA P10253 2/20 0.47
LMNA P02545 2/20 0.47
POLB P06746 2/20 0.47
NFKB1 P19838 1/20 0.47
XDH P47989 1/20 0.47
GFER P55789 1/20 0.47
NFKB2 Q00653 1/20 0.47
RELA Q04206 1/20 0.47
FUT7 Q11130 1/20 0.47
TDP1 Q9NUW8 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4576605 0.82 CA12 (0.62) CA1CA2CA12CA7CA9
SCHEMBL31556006 0.82 HSD17B2 (0.58) MAPTKDM4EALDH1A1CA1CA2
SCHEMBL11852308 0.81 MAPT (0.44) MAPTKDM4EALDH1A1CA1CA2
SCHEMBL29149098 0.81 EGFR (0.45) MAPTKDM4EALDH1A1CA1CA2
SCHEMBL2937093 0.81 CA12 (0.41) KDM4EALDH1A1CA1CA2CA12
SCHEMBL4576891 0.81 CA12 (0.41) KDM4EALDH1A1CA1CA2CA12
SCHEMBL31556004 0.80 ALDH1A1 (0.51) MAPTKDM4EALDH1A1CA1CA2
SCHEMBL18288084 0.80 CYP3A4 (0.43) MAPTKDM4EALDH1A1CNR2POLB
SCHEMBL31238916 0.79 CNR2 (0.62) MAPTKDM4EALDH1A1CA1CA2
SCHEMBL11857045 0.79 MAPT (0.45) MAPTKDM4EALDH1A1CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112851506-A Industrial preparation method of 3, 5-dimethoxy, 4-alkyl benzyl alcohol 湖北英纳氏生物科技有限公司 2021-05-28 CN claimed
CN-122029153-A Aromatic hydrocarbon receptor modulator compound, and preparation method and application thereof 德明药泰生物技术(深圳)有限公司 2026-05-12 CN disclosed
WO-2025099634-A1 PROCESS FOR PREPARING THE POLYMORPHIC FORM III OF TAPINAROF PROCOS S.P.A. (IT) 2025-05-15 WO disclosed
WO-2025082312-A1 AROMATIC HYDROCARBON RECEPTOR MODULATOR COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF 德明药泰生物技术(深圳)有限公司 2025-04-24 WO disclosed
CN-114957171-B Novel five-membered heterocycle substituted styrene derivative and preparation method and application thereof 广东工业大学 2024-07-30 CN disclosed
CN-117447402-A Aromatic hydrocarbon receptor modulator compound, and preparation method and application thereof 德明药泰生物技术(深圳)有限公司 2024-01-26 CN disclosed
CN-112851506-B Industrial preparation method of 3, 5-dimethoxy-4-alkyl benzyl alcohol 湖北英纳氏生物科技有限公司 2023-06-23 CN disclosed
CN-114957171-A Novel five-membered heterocyclic substituted styrene derivative and preparation method and application thereof 广东工业大学 2022-08-30 CN disclosed
EP-3608308-B1 LIPIDS AND LIPID COMPOSITIONS FOR THE DELIVERY OF ACTIVE AGENTS NOVARTIS AG (CH) 2021-07-21 EP disclosed
CN-113072488-A Styrene derivative and synthesis method and application thereof 广东工业大学 2021-07-06 CN disclosed
US-20080139666-A1 Anti-Inflammatory and Psoriasis Treatment and Protein Kinase Inhibition by Hydroxy Stilbenes and Novel Stilbene Derivatives and Analogues WELICHEM BIOTECH INC. (CA) 2008-06-12 US disclosed
US-20080139666-A1 Anti-Inflammatory and Psoriasis Treatment and Protein Kinase Inhibition by Hydroxy Stilbenes and Novel Stilbene Derivatives and Analogues WELICHEM BIOTECH INC. (CA) 2008-06-12 US disclosed
US-7321050-B2 Anti-inflammatory and psoriasis treatment and protein kinase inhibition by hydroxy stilbenes and novel stilbene derivatives and analogues WELICHEM BIOTECH INC. (CA) 2008-01-22 US disclosed
US-7321050-B2 Anti-inflammatory and psoriasis treatment and protein kinase inhibition by hydroxy stilbenes and novel stilbene derivatives and analogues WELICHEM BIOTECH INC. (CA) 2008-01-22 US disclosed
US-7321050-B2 Anti-inflammatory and psoriasis treatment and protein kinase inhibition by hydroxy stilbenes and novel stilbene derivatives and analogues WELICHEM BIOTECH INC. (CA) 2008-01-22 US disclosed
US-20050059733-A1 Anti-inflammatory and psoriasis treatment and protein kinase inhibition by hydroxy stilbenes and novel stilbene derivatives and analogues WELICHEM BIOTECH, INC. 2005-03-17 US disclosed
US-20040102517-A1 Modulators of T- cells, neutrophils, macrophages and their associated cytokines GLAXO GROUP LIMITED (GB) 2004-05-27 US disclosed
US-20030171429-A1 Anti-inflammatory and psoriasis treatment and protein kinase inhibition by hydroxyltilbenes and novel stilbene derivatives and analogues WELICHEMBIOTECH INC. (CA) 2003-09-11 US disclosed
EP-1248774-A2 POLYHYDROXYSTILBENES AND STILBENE OXIDES AS ANTIPSORIATIC AGENTS AND PROTEIN KINASE INHIBITORS Welichem Biotech Inc. (CA) 2002-10-16 EP disclosed
WO-2001042231-A2 POLYHYDROXYSTILBENES AND STILBENE OXIDES AS ANTISORIATIC AGENTS AND PROTEIN KINASE INHIBITORS WELICHEM BIOTECH INC. (CA) 2001-06-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050059733-A1 Anti-inflammatory and psoriasis treatment and protein kinase inhibition by hydroxy stilbenes and novel stilbene derivatives and analogues NFKBIA, IKBKB, IKBKE MAPT 1005/4885KDM4E 1128/4885ALDH1A1 3063/4885
US-20040102517-A1 Modulators of T- cells, neutrophils, macrophages and their associated cytokines IL2, NFATC1, IFNG MAPT 1655/4885KDM4E 1923/4885ALDH1A1 2595/4885
US-20080139666-A1 Anti-Inflammatory and Psoriasis Treatment and Protein Kinase Inhibition by Hydroxy Stilbenes and Novel Stilbene Derivatives and Analogues LTK, MMP8, CHUK MAPT 1243/4885KDM4E 3937/4885ALDH1A1 4482/4885
US-20030171429-A1 Anti-inflammatory and psoriasis treatment and protein kinase inhibition by hydroxyltilbenes and novel stilbene derivatives and analogues ROCK1, ROCK2, PTK2 MAPT 2917/4885KDM4E 1871/4885ALDH1A1 3304/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.