SCHEMBL8664097

SCHEMBL8664097

Cc1cccc(NC(=O)Nc2ccc(S(=O)(=O)NC(=O)c3ccc4ccccc4c3)cc2)c1

nearest known ligand 0.66

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
GPR27 Q9NS67 1/20 0.58
RAB9A P51151 5/20 0.55
NPC1 O15118 4/20 0.55
KMT2A Q03164 3/20 0.55
MEN1 O00255 2/20 0.55
L3MBTL1 Q9Y468 1/20 0.55
ENPP2 Q13822 1/20 0.53
CA2 P00918 1/20 0.52
KAT6A Q92794 1/20 0.52
LMNA P02545 2/20 0.51
GHSR Q92847 1/20 0.50
MAPT P10636 1/20 0.50
POLB P06746 1/20 0.49
IMPDH2 P12268 1/20 0.48
IDO1 P14902 1/20 0.48
APOBEC3G Q9HC16 1/20 0.48
TSHR P16473 1/20 0.48
SAE1 Q9UBE0 1/20 0.48
UBA2 Q9UBT2 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8912421 0.92 GPR27 (0.56) GPR27RAB9ANPC1KMT2AMEN1
SCHEMBL7776124 0.91 ENPP2 (0.64) GPR27RAB9ANPC1KMT2AMEN1
SCHEMBL8658196 0.90 GPR27 (0.71) GPR27RAB9ANPC1ENPP2CA2
SCHEMBL7770076 0.89 RAB9A (0.56) RAB9ANPC1KMT2AMEN1KAT6A
SCHEMBL8768061 0.88 RAB9A (0.64) GPR27RAB9ANPC1KMT2AMEN1
SCHEMBL8658342 0.88 LMNA (0.60) RAB9ANPC1KMT2AMEN1L3MBTL1
SCHEMBL8667069 0.88 LMNA (0.60) RAB9ANPC1KMT2AMEN1CA2
SCHEMBL8766875 0.83 NPC1 (0.62) GPR27RAB9ANPC1KMT2AMEN1
SCHEMBL9176194 0.82 KAT6A (0.64) GPR27RAB9ANPC1KMT2AMEN1
SCHEMBL7776320 0.82 ENPP2 (0.61) GPR27RAB9ANPC1ENPP2KAT6A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0699662-B1 Novel urea (thiourea) derivative and thermal recording sheet using same JUJO PAPER CO LTD (JP) 1998-10-21 EP disclosed
US-5661100-A HAVING HIGH SENSITIVITY, SUPERIOR THERMAL RESISTANCE, WATER RESISTANCE, OIL RESISTANCE NIPPON PAPER INDUSTRIES CO., LTD. (JP) 1997-08-26 US disclosed
EP-0699662-A1 Novel urea (thiourea) derivative and thermal recording sheet using same NIPPON PAPER INDUSTRIES CO., LTD. (JP) 1996-03-06 EP disclosed