Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 3/20 | 0.64 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.64 |
| ▸ | IDO1 | P14902 | 5/20 | 0.56 |
| ▸ | CSNK2A1 | P68400 | 9/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.52 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.47 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.46 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.46 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL112200 | 0.97 | PNMT (0.67) | PNMTTAAR1IDO1CSNK2A1SIGMAR1 | |
| SCHEMBL29349576 | 0.97 | PNMT (0.67) | PNMTTAAR1IDO1CSNK2A1SIGMAR1 | |
| Hydrochloric Acid SCHEMBL3127848 | 0.95 | PNMT (0.64) | PNMTTAAR1IDO1CSNK2A1SIGMAR1 | |
| SCHEMBL5558540 | 0.79 | TAAR1 (0.62) | PNMTTAAR1IDO1CSNK2A1SIGMAR1 | |
| SCHEMBL8349185 | 0.79 | KDM4E (0.56) | PNMTTAAR1IDO1CSNK2A1SIGMAR1 | |
| SCHEMBL8847353 | 0.78 | PNMT (0.50) | PNMTTAAR1CSNK2A1LOXL2CSNK2A2 | |
| SCHEMBL22118869 | 0.78 | PNMT (0.61) | PNMTTAAR1IDO1SIGMAR1 | |
| SCHEMBL879052 | 0.78 | CYP3A4 (0.71) | PNMTTAAR1CSNK2A1LOXL2CSNK2A2 | |
| SCHEMBL184185 | 0.78 | TAAR1 (1.00) | PNMTTAAR1IDO1SIGMAR1 | |
| SCHEMBL29467979 | 0.78 | CYP3A4 (0.71) | PNMTTAAR1CSNK2A1LOXL2CSNK2A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0434213-B1 | Monosubstituted dithiooxamide compounds and their use | MINNESOTA MINING & MFG (US) | 1995-04-05 | — | — | EP | disclosed |
| US-5124308-A | Reacts with transition metal salt for carbonless paper copying | MINNESOTA MINING AND MANUFACTURING COMPANY | 1992-06-23 | — | — | US | disclosed |
| US-5041654-A | Transamination in wallach reaction; controlling temperature; reactant amine concentration | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1991-08-20 | — | — | US | disclosed |
| EP-0434213-A1 | Monosubstituted dithiooxamide compounds and their use | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1991-06-26 | — | — | EP | disclosed |
| EP-0431783-A1 | Preparation of monosubstituted dithiooxamide compounds | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1991-06-12 | — | — | EP | disclosed |