Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 known ✓ | Q99720 | 2/20 | 0.52 |
| ▸ | PNMT | P11086 | 3/20 | 0.64 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.64 |
| ▸ | IDO1 | P14902 | 5/20 | 0.59 |
| ▸ | CSNK2A1 | P68400 | 9/20 | 0.57 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL112200 | 0.97 | PNMT (0.67) | PNMTTAAR1IDO1CSNK2A1SIGMAR1 | |
| SCHEMBL29349576 | 0.97 | PNMT (0.67) | PNMTTAAR1IDO1CSNK2A1SIGMAR1 | |
| Ammonia Solution, Strong SCHEMBL9178453 | 0.95 | PNMT (0.64) | PNMTTAAR1IDO1CSNK2A1SIGMAR1 | |
| Hydrochloric Acid SCHEMBL28342342 | 0.81 | TP53 (0.50) | PNMTTAAR1IDO1CSNK2A1LOXL2 | |
| Hydrochloric Acid SCHEMBL2540390 | 0.81 | TAAR1 (0.95) | PNMTTAAR1IDO1SIGMAR1 | |
| Hydrochloric Acid SCHEMBL30496706 | 0.81 | TAAR1 (0.95) | PNMTTAAR1IDO1SIGMAR1 | |
| SCHEMBL5558540 | 0.79 | TAAR1 (0.62) | PNMTTAAR1IDO1CSNK2A1SIGMAR1 | |
| Hydrochloric Acid SCHEMBL5958057 | 0.79 | CSNK2A1 (0.47) | PNMTTAAR1IDO1CSNK2A1SIGMAR1 | |
| Hydrochloric Acid SCHEMBL8975991 | 0.79 | CSNK2A1 (0.52) | PNMTTAAR1IDO1CSNK2A1LOXL2 | |
| Hydrochloric Acid SCHEMBL4725966 | 0.79 | CSNK2A1 (0.53) | PNMTTAAR1IDO1CSNK2A1LOXL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2729169-A1 | HUMAN RESPIRATORY SYNCYTIAL VIRUS VACCINE | Nanobio Corporation (US) | 2014-05-14 | — | — | EP | claimed |
| WO-2013006797-A1 | HUMAN RESPIRATORY SYNCYTIAL VIRUS VACCINE | NANOBIO CORPORATION (US) | 2013-01-10 | — | — | WO | claimed |
| US-4022880-A | ZINC IONS, 3,4,5-TRIBROMO-SALICYLANILIDE, QUATERNARY AMMONIUM COMPOUNDS | LEVER BROTHERS COMPANY (US) | 1977-05-10 | — | — | US | claimed |
| CN-118042960-A | Filaments for oral care implements | 联合利华知识产权控股有限公司 | 2024-05-14 | — | — | CN | disclosed |
| EP-3628404-B1 | PIPETTE TIP TRAYS | BIOTIX INC (US) | 2021-06-30 | — | — | EP | disclosed |
| EP-3831489-A1 | PIPETTE TIPS | Biotix, Inc. (US) | 2021-06-09 | — | — | EP | disclosed |
| US-20210016290-A1 | PIPETTE TIP RACK | BIOTIX, INC. | 2021-01-21 | — | — | US | disclosed |
| EP-2525910-B1 | PIPETTE TIPS | BIOTIX INC (US) | 2020-12-09 | — | — | EP | disclosed |
| US-10828633-B2 | Pipette tips | BIOTIX, INC. (US) | 2020-11-10 | — | — | US | disclosed |
| US-10737273-B2 | Pipette tip rack | BIOTIX, INC. (US) | 2020-08-11 | — | — | US | disclosed |
| EP-3653303-A1 | PIPETTE TIP RACK | Biotix, Inc. (US) | 2020-05-20 | — | — | EP | disclosed |
| WO-2010008737-A2 | ANTIMICROBIAL FLUID HANDLING DEVICES AND METHODS OF MANUFACTURE | PELICAN GROUP HOLDINGS, INC. (US) | 2010-01-21 | — | — | WO | disclosed |
| US-5846215-A | Antibacterial swabs | CHESEBROUGH-POND'S USA CO., DIVISION OF CONOPCO, INC. (US) | 1998-12-08 | — | — | US | disclosed |
| EP-0507317-B1 | Biguanide derivatives, manufacturing method thereof, and disinfectants containing the derivatives | OTSUKA PHARMA CO LTD (JP) | 1997-01-15 | — | — | EP | disclosed |
| US-5376686-A | Human, animal, medical equipment | OTSUKA PHARMACEUTICAL CO., LTD. | 1994-12-27 | — | — | US | disclosed |
| EP-0290558-B1 | ANTIFOLATE AGENTS | BTG INTERNATIONAL LIMITED (GB) | 1993-06-16 | — | — | EP | disclosed |
| EP-0507317-A2 | Biguanide derivatives, manufacturing method thereof, and disinfectants containing the derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1992-10-07 | — | — | EP | disclosed |
| US-4992444-A | Antitumor agents, skin disorders | BRITISH TECHNOLOGY GROUP LIMITED (GB) | 1991-02-12 | — | — | US | disclosed |
| EP-0290558-A1 | ANTIFOLATE AGENTS. | STEVENS MALCOLM FRANCIS GRAHAM (GB) | 1988-11-17 | — | — | EP | disclosed |
| WO-1988004293-A1 | ANTIFOLATE AGENTS | STEVENS MALCOLM FRANCIS GRAHAM (GB) | 1988-06-16 | — | — | WO | disclosed |