Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | FYN | P06241 | 2/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 6/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.34 |
| ▸ | DUT | P33316 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9022828 | 0.80 | CYP4F2 (0.52) | TSHRCACNA1B | |
| SCHEMBL9214800 | 0.79 | DUT (0.37) | FFAR1ALOX5HRH4HRH3DUT | |
| SCHEMBL4751293 | 0.77 | FYN (0.38) | GRM5L3MBTL1FFAR1FYNTSHR | |
| SCHEMBL9179775 | 0.76 | ALOX5 (0.55) | ALOX5 | |
| SCHEMBL3197958 | 0.76 | SOD1 (0.51) | L3MBTL1FFAR1ALOX5 | |
| SCHEMBL9458246 | 0.76 | SOD1 (0.37) | L3MBTL1FFAR1FYNALOX5HRH4 | |
| SCHEMBL1040476 | 0.74 | L3MBTL1 (0.55) | L3MBTL1KDM4E | |
| SCHEMBL9185048 | 0.73 | ALOX5 (0.38) | L3MBTL1FFAR1ALOX5MAPK1CACNA1B | |
| SCHEMBL1607526 | 0.73 | MAOB (0.48) | FFAR1TSHRMAPK1KDM4E | |
| SCHEMBL9365359 | 0.72 | MAOB (0.52) | TSHRCACNA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0375368-B1 | Alcohol and ether derivatives | ZENECA LTD (GB) | 1995-08-16 | — | — | EP | disclosed |
| EP-0385680-B1 | Heterocyclic ethers as 5-lipoxygenase inhibitors | ZENECA LTD (GB) | 1995-06-14 | — | — | EP | disclosed |
| US-5214069-A | Lipoxygenase inhibitors | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-05-25 | — | — | US | disclosed |
| US-5202326-A | Inhibitor of enzyme 5-lipoxygenase; antiinflammatory and antiallergic agents | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-04-13 | — | — | US | disclosed |
| US-5132328-A | Lipoxygenase inhibitors as antiinflammatory agents or antiallergens | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-07-21 | — | — | US | disclosed |
| EP-0385680-A2 | Heterocyclic ethers as 5-lipoxygenase inhibitors | ZENECA LIMITED (GB) | 1990-09-05 | — | — | EP | disclosed |
| EP-0375368-A2 | Alcohol and ether derivatives | ZENECA LIMITED (GB) | 1990-06-27 | — | — | EP | disclosed |