Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOD1 | P00441 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.34 |
| ▸ | FYN | P06241 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.33 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.33 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21635605 | 0.83 | ESR1 (0.39) | L3MBTL1AOC3 | |
| SCHEMBL3197958 | 0.82 | SOD1 (0.51) | SOD1L3MBTL1LMNAPOLBHTT | |
| SCHEMBL9458177 | 0.81 | SOD1 (0.37) | SOD1L3MBTL1LMNAPOLBHTT | |
| SCHEMBL5417589 | 0.77 | PKM (0.45) | SOD1LMNAPKMKDM4EFFAR1 | |
| SCHEMBL1040476 | 0.77 | L3MBTL1 (0.55) | L3MBTL1LMNAPOLBPKMKDM4E | |
| SCHEMBL9182146 | 0.76 | GRM5 (0.39) | L3MBTL1KDM4EFFAR1FYNALOX5 | |
| SCHEMBL9185048 | 0.76 | ALOX5 (0.38) | SOD1L3MBTL1LMNAPOLBHTT | |
| SCHEMBL1607526 | 0.75 | MAOB (0.48) | LMNAKDM4EFFAR1MAOB | |
| SCHEMBL3906704 | 0.75 | PKM (0.43) | SOD1LMNAPKMKDM4EFFAR1 | |
| SCHEMBL3420663 | 0.74 | CHRNB2 (0.56) | LMNACHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5202326-A | Inhibitor of enzyme 5-lipoxygenase; antiinflammatory and antiallergic agents | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-04-13 | — | — | US | disclosed |
| EP-0385680-A2 | Heterocyclic ethers as 5-lipoxygenase inhibitors | ZENECA LIMITED (GB) | 1990-09-05 | — | — | EP | disclosed |