SCHEMBL918265

SCHEMBL918265

Nc1ccccc1-c1ccc(Br)cc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.65
HSD17B10 Q99714 1/20 0.65
L3MBTL1 Q9Y468 1/20 0.55
MAPK1 P28482 3/20 0.50
NPC1 O15118 3/20 0.47
GAA P10253 3/20 0.47
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47
PLK4 O00444 1/20 0.44
AURKA O14965 1/20 0.44
JAK2 O60674 1/20 0.44
LCK P06239 1/20 0.44
CDK1 P06493 1/20 0.44
CSF1R P07333 1/20 0.44
LYN P07948 1/20 0.44
FGFR1 P11362 1/20 0.44
SRC P12931 1/20 0.44
PRKACA P17612 1/20 0.44
RPS6KB1 P23443 1/20 0.44
CDK2 P24941 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25547292 0.88 ALDH1A1 (0.52) ALDH1A1HSD17B10L3MBTL1MAPK1NPC1
SCHEMBL6480845 0.87 ALDH1A1 (0.83) ALDH1A1HSD17B10L3MBTL1NPC1GAA
SCHEMBL31264295 0.85 ALDH1A1 (0.79) ALDH1A1HSD17B10L3MBTL1NPC1GAA
SCHEMBL19125933 0.82 ALDH1A1 (0.63) ALDH1A1MAPK1NPC1GAAMEN1
SCHEMBL7522172 0.82 ALDH1A1 (0.63) ALDH1A1MAPK1NPC1GAAMEN1
SCHEMBL28281037 0.81 ALDH1A1 (0.62) ALDH1A1HSD17B10MAPK1NPC1GAA
SCHEMBL15954483 0.80 PLK4 (0.45) ALDH1A1HSD17B10L3MBTL1MAPK1NPC1
SCHEMBL29510158 0.80 ALDH1A1 (0.71) ALDH1A1HSD17B10L3MBTL1NPC1GAA
SCHEMBL599657 0.80 ALDH1A1 (0.71) ALDH1A1HSD17B10L3MBTL1NPC1GAA
SCHEMBL712916 0.80 ALDH1A1 (0.90) ALDH1A1HSD17B10L3MBTL1MAPK1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 109 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119505419-B Anti-aging reinforced PP (Polypropylene) daily plastic product and preparation method thereof 广东百文科技实业有限公司 2025-06-03 CN claimed
CN-119505419-A Anti-aging reinforced PP (Polypropylene) daily plastic product and preparation method thereof 广东百文科技实业有限公司 2025-02-25 CN claimed
CN-115716787-B Alkyl fluorene small molecular compound and preparation method and application thereof 天津大学 2024-02-13 CN claimed
CN-117448062-A Aromatic amine polyurea hub bearing lubricating grease and preparation method thereof 安徽腾盛化学有限公司 2024-01-26 CN claimed
CN-115716787-A Alkyl fluorene micromolecule compound and preparation method and application thereof 天津大学 2023-02-28 CN claimed
EP-1819223-B1 USE OF MENADIONE FOR BOOSTING THE EFFECTIVENESS OF AGROCHEMICALS BASF SE (DE) 2008-03-12 EP claimed
EP-1360176-B1 PYRROLECARBOXAMIDES FOR USE AS FUNGICIDES SYNGENTA PARTICIPATIONS AG (CH) 2006-11-02 EP claimed
US-20040082477-A1 Pyrrolecarboxamides for the use as fungicdes SYNGENTA CROP PROTECTION, INC. 2004-04-29 US claimed
EP-1360176-A1 PYRROLECARBOXAMIDES FOR USE AS FUNGICIDES Syngenta Participations AG (CH) 2003-11-12 EP claimed
WO-2002064562-A1 PYRROLECARBOXAMIDES FOR THE USE AS FUNGICIDES SYNGENTA PARTICIPATIONS AG (CH) 2002-08-22 WO claimed
CN-121974848-A Quinoline anti-aging agent and preparation method thereof 山东阳谷华泰化工股份有限公司 2026-05-05 CN disclosed
CN-119505419-B Anti-aging reinforced PP (Polypropylene) daily plastic product and preparation method thereof 广东百文科技实业有限公司 2025-06-03 CN disclosed
CN-119955091-A Polymer, positive-type negative-type photosensitive resin composition, pattern forming method, cured film forming method, interlayer insulating film, surface protective film, and electronic component 信越化学工业株式会社 2025-05-09 CN disclosed
CN-119505419-A Anti-aging reinforced PP (Polypropylene) daily plastic product and preparation method thereof 广东百文科技实业有限公司 2025-02-25 CN disclosed
CN-115124540-B Organic compound and organic electroluminescent device 江苏绿人半导体有限公司 2024-06-07 CN disclosed
WO-2002064562-A1 PYRROLECARBOXAMIDES FOR THE USE AS FUNGICIDES SYNGENTA PARTICIPATIONS AG (CH) 2002-08-22 WO disclosed
WO-2002059086-A1 CARBOXAMIDES AS FUNGICIDES IN AGRICULTURE SYNGENTA PARTICIPATIONS AG (CH) 2002-08-01 WO disclosed
US-6369093-B1 Pyrazole carboxanilide fungicide BAYER AKTIENGESELLSCHAFT (DE) 2002-04-09 US disclosed
EP-1161420-A2 FUNGICIDAL PYRAZOLE CARBOXANILIDES Bayer Aktiengesellschaft (DE) 2001-12-12 EP disclosed
WO-2000014071-A2 PYRAZOLE CARBOXANILIDE FUNGICIDE BAYER AKTIENGESELLSCHAFT (DE) 2000-03-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040082477-A1 Pyrrolecarboxamides for the use as fungicdes CBR3, HPD, BROX ALDH1A1 1697/4885HSD17B10 2332/4885L3MBTL1 2502/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.