Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPN | P05981 | 1/20 | 0.43 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9184400 | 0.82 | MT-CO2 (0.42) | MEN1KMT2AGAAALDH1A1SMN1; SMN2 | |
| SCHEMBL9181710 | 0.80 | ALDH1A1 (0.42) | MEN1KMT2AALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL9188796 | 0.78 | CNR1 (0.43) | KMT2A | |
| SCHEMBL9184952 | 0.72 | AR (0.42) | PDE4BPDE4D | |
| SCHEMBL3422385 | 0.70 | HPN (0.47) | HPNSCN2AMEN1KMT2AGAA | |
| SCHEMBL11825117 | 0.67 | HPN (0.41) | HPNSCN2AMEN1KMT2AGAA | |
| SCHEMBL11790251 | 0.66 | SCN2A (0.62) | HPNSCN2AMEN1KMT2AGAA | |
| SCHEMBL11787449 | 0.65 | SCN2A (0.61) | HPNSCN2AMEN1KMT2AGAA | |
| SCHEMBL10854270 | 0.64 | HPN (0.68) | HPNSCN2AMEN1KMT2AGAA | |
| SCHEMBL3190715 | 0.64 | HPN (0.55) | HPNSCN2AMEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0455300-B1 | Barbituric acid derivatives having insecticidal activity | DUPHAR INT RES (NL) | 1995-06-28 | — | — | EP | disclosed |
| US-5164396-A | Control of aphids | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1992-11-17 | — | — | US | disclosed |
| EP-0455300-A1 | Barbituric acid derivatives having insecticidal activity | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1991-11-06 | — | — | EP | disclosed |