Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 9/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CCKBR | P32239 | 1/20 | 0.38 |
| ▸ | ACACB | O00763 | 1/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9181710 | 0.85 | ALDH1A1 (0.42) | CNR1CNR2NOTUMKMT2A | |
| SCHEMBL9181360 | 0.83 | CCKBR (0.38) | CHRM4NOTUMFFAR4DRD2DRD3 | |
| SCHEMBL9186146 | 0.82 | FAAH (0.39) | DRD2DRD3KCNH2KMT2A | |
| SCHEMBL9184400 | 0.81 | MT-CO2 (0.42) | KMT2A | |
| SCHEMBL9188526 | 0.79 | MCHR1 (0.40) | CHRM4NOTUMDRD2DRD3KCNH2 | |
| SCHEMBL9181349 | 0.77 | NOTUM (0.37) | CHRM4NOTUMFFAR4DRD2DRD3 | |
| SCHEMBL9182339 | 0.76 | TRPA1 (0.42) | CNR1 | |
| SCHEMBL9184952 | 0.73 | AR (0.42) | CHRM4DRD2DRD3KCNH2CHRM2 | |
| SCHEMBL9186350 | 0.72 | FFAR4 (0.36) | CHRM4FFAR4DRD2DRD3CHRM2 | |
| SCHEMBL7607513 | 0.66 | MCHR1 (0.53) | NOTUMFFAR4DRD2DRD3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0455300-B1 | Barbituric acid derivatives having insecticidal activity | DUPHAR INT RES (NL) | 1995-06-28 | — | — | EP | disclosed |
| US-5164396-A | Control of aphids | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1992-11-17 | — | — | US | disclosed |
| EP-0455300-A1 | Barbituric acid derivatives having insecticidal activity | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1991-11-06 | — | — | EP | disclosed |