SCHEMBL9185083

SCHEMBL9185083

CN(C)c1ccc(C=O)c(S(C)(=O)=O)c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 1/20 0.42
CYP2A13 Q16696 1/20 0.42
ALDH1A1 P00352 5/20 0.37
KDM4E B2RXH2 1/20 0.37
GAA P10253 1/20 0.37
PDE3B Q13370 1/20 0.37
PDE3A Q14432 1/20 0.37
TERT O14746 1/20 0.37
APP P05067 1/20 0.37
ACHE P22303 2/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
PSMB5 P28074 1/20 0.35
IP6K1 Q92551 1/20 0.35
PTGS2 P35354 3/20 0.35
BCHE P06276 1/20 0.35
TSHR P16473 3/20 0.34
HSD17B10 Q99714 2/20 0.34
ALOX15 P16050 2/20 0.34
TP53 P04637 1/20 0.34
MAPK1 P28482 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12593470 0.76 SMN1; SMN2 (0.52) ALDH1A1PTGS2NPC1RAB9A
SCHEMBL4444489 0.76 ALDH1A1 (0.42) CYP2A6ALDH1A1KDM4EGAAL3MBTL1
SCHEMBL2600014 0.74 TDP1 (0.53) ALDH1A1KDM4EACHE
SCHEMBL14735611 0.74 RAD51 (0.49) ALDH1A1L3MBTL1MEN1KMT2A
SCHEMBL14741400 0.74 CYP2A6 (0.45) CYP2A6CYP2A13ALDH1A1KDM4EGAA
SCHEMBL6076943 0.74 KDM4E (0.41) ALDH1A1KDM4EPTGS2
SCHEMBL1793926 0.74 ERN1 (0.46) CYP2A6ALDH1A1TSHRCA12CA2
SCHEMBL8964348 0.73 CYP2A6 (0.48) CYP2A6CYP2A13ALDH1A1KDM4EGAA
SCHEMBL143348 0.73 CYP2A6 (0.48) CYP2A6CYP2A13ALDH1A1KDM4EGAA
SCHEMBL7671562 0.73 CYP2A6 (0.48) CYP2A6CYP2A13ALDH1A1KDM4EGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0453395-B1 Pressure sensitive recording material CIBA GEIGY AG (CH) 1995-11-02 EP disclosed
US-5254522-A Pressure-sensitive or heat-sensitive recording material CIBA-GEIGY CORPORATION (US) 1993-10-19 US disclosed
EP-0453395-A1 Pressure sensitive recording material CIBA-GEIGY AG (CH) 1991-10-23 EP disclosed