Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP1 | O94782 | 11/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9186353 | 0.87 | USP1 (0.36) | USP1KMT2AACHE | |
| SCHEMBL7435529 | 0.70 | AGTR1 (0.44) | NPSR1MEN1KMT2ALMNATSHR | |
| SCHEMBL31398271 | 0.67 | PARK7 (0.46) | MEN1KMT2AACHEALDH1A1MAPT | |
| SCHEMBL30489385 | 0.65 | ALDH1A1 (0.53) | MEN1KMT2AACHEALDH1A1MAPT | |
| SCHEMBL28995174 | 0.65 | ALDH1A1 (0.53) | MEN1KMT2AACHEALDH1A1MAPT | |
| SCHEMBL31414463 | 0.61 | XIAP (0.51) | MEN1KMT2ALMNARAB9A | |
| SCHEMBL26604864 | 0.61 | XIAP (0.51) | MEN1KMT2ALMNARAB9A | |
| SCHEMBL30489292 | 0.61 | POLB (0.55) | MEN1KMT2AALDH1A1POLB | |
| SCHEMBL29839407 | 0.61 | CMA1 (0.58) | MEN1KMT2ALMNATSHRALDH1A1 | |
| SCHEMBL28995159 | 0.61 | POLB (0.55) | MEN1KMT2AALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5466692-A | Substituted pyridopyrimidines and antihypertensives | AMERICAN HOME PRODUCTS CORPORATION (US) | 1995-11-14 | — | — | US | disclosed |