Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.41 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | PRKCI | P41743 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 2/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL918599 | 1.00 | L3MBTL1 (0.50) | L3MBTL1ALDH1A1MAPTMAPK1KDM4E | |
| SCHEMBL917447 | 0.78 | ALDH1A1 (0.42) | L3MBTL1ALDH1A1MAPTMAPK1KDM4E | |
| SCHEMBL917448 | 0.78 | ALDH1A1 (0.42) | L3MBTL1ALDH1A1MAPTMAPK1KDM4E | |
| SCHEMBL918023 | 0.78 | ALDH1A1 (0.47) | L3MBTL1ALDH1A1MAPTMAPK1KDM4E | |
| SCHEMBL918025 | 0.78 | ALDH1A1 (0.47) | L3MBTL1ALDH1A1MAPTMAPK1KDM4E | |
| SCHEMBL12904894 | 0.78 | ALDH1A1 (0.47) | L3MBTL1ALDH1A1MAPTMAPK1KDM4E | |
| Acetic Acid SCHEMBL1228744 | 0.78 | L3MBTL1 (0.48) | L3MBTL1ALDH1A1MAPTMAPK1KDM4E | |
| Acetic Acid SCHEMBL1228968 | 0.76 | L3MBTL1 (0.46) | L3MBTL1ALDH1A1MAPTMAPK1KDM4E | |
| Acetic Acid SCHEMBL1228946 | 0.75 | L3MBTL1 (0.45) | L3MBTL1ALDH1A1MAPTMAPK1KDM4E | |
| Acetic Acid SCHEMBL1229848 | 0.74 | L3MBTL1 (0.44) | L3MBTL1ALDH1A1MAPTMAPK1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9273024-B2 | Synthesis of cyclic carbonates | UNIVERSITY OF YORK (GB) | 2016-03-01 | — | — | US | disclosed |
| EP-2257559-B1 | SYNTHESIS OF CYCLIC CARBONATES | UNIV YORK (GB) | 2014-10-15 | — | — | EP | disclosed |
| US-20130317237-A1 | SYNTEHSIS OF CYCLIC CARBONATES | UNIVERSITY OF NEW CASTLE UPON TYNE (GB) | 2013-11-28 | — | — | US | disclosed |
| US-20110015409-A1 | SYNTHESIS OF CYCLIC CARBONATES | UNIVERSITY OF NEWCASTLE UPON TYNE (GB) | 2011-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130317237-A1 | SYNTEHSIS OF CYCLIC CARBONATES | CA12, SUCLA2, LMNA | L3MBTL1 1301/4885ALDH1A1 3080/4885MAPT 4780/4885 |
| US-20110015409-A1 | SYNTHESIS OF CYCLIC CARBONATES | NR3C2, NR2C2, NR3C1 | L3MBTL1 2864/4885ALDH1A1 3200/4885MAPT 4670/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.