Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK13 | O15264 | 1/20 | 0.44 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.44 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.44 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | PLK1 | P53350 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14899868 | 0.84 | IDO1 (0.52) | ALDH1A1HPGDLMNAIDO1SMN1; SMN2 | |
| SCHEMBL1200737 | 0.84 | SRD5A2 (0.48) | MAPK13MAPK12MAPK11MAPK14SRD5A2 | |
| SCHEMBL52136 | 0.84 | ALDH1A1 (0.52) | MAPK13MAPK12MAPK11MAPK14SRD5A2 | |
| SCHEMBL9186881 | 0.82 | ALDH1A1 (0.42) | MAPK13MAPK12MAPK11MAPK14SRD5A2 | |
| SCHEMBL25652847 | 0.76 | ALDH1A1 (0.70) | SRD5A2ALDH1A1RAB9ALMNAHDAC1 | |
| SCHEMBL8666599 | 0.76 | MAPK13 (0.67) | MAPK13MAPK12MAPK11MAPK14SRD5A2 | |
| SCHEMBL15025047 | 0.76 | SRD5A2 (0.41) | MAPK13MAPK12MAPK11MAPK14SRD5A2 | |
| SCHEMBL6659142 | 0.76 | SRD5A2 (0.65) | SRD5A2ALDH1A1TP53 | |
| SCHEMBL4541127 | 0.76 | ALDH1A1 (0.61) | MAPK13MAPK12MAPK11MAPK14SRD5A2 | |
| SCHEMBL8091787 | 0.75 | IDO1 (0.67) | SRD5A2ALDH1A1HPGDRAB9AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0315140-B1 | Non-linear optical device | HITACHI LTD (JP) | 1995-08-23 | — | — | EP | disclosed |
| US-5176854-A | Xanthone Derivatives | HITACHI, LTD. (JP) | 1993-01-05 | — | — | US | disclosed |
| EP-0315140-A2 | Non-linear optical device | HITACHI, LTD. (JP) | 1989-05-10 | — | — | EP | disclosed |