Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 6/20 | 0.50 |
| ▸ | CA2 | P00918 | 6/20 | 0.50 |
| ▸ | CA9 | Q16790 | 3/20 | 0.50 |
| ▸ | CA12 | O43570 | 2/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8514633 | 0.89 | CA2 (0.59) | CA1CA2CA9CA12CYP19A1 | |
| SCHEMBL818508 | 0.82 | HTR6 (0.50) | MAPT | |
| SCHEMBL161783 | 0.81 | HTR6 (0.61) | CA1CA2CA9CA12CYP19A1 | |
| SCHEMBL29337050 | 0.79 | IDO1 (0.62) | CA1CA2CA9CA12CYP19A1 | |
| SCHEMBL9192526 | 0.79 | CA1 (0.50) | CA1CA2CA9CA12CYP19A1 | |
| SCHEMBL14378095 | 0.79 | ALDH1A1 (0.67) | CA1CA2CA9CA12BCHE | |
| SCHEMBL160164 | 0.79 | CA1 (0.50) | CA1CA2CA9CA12CYP19A1 | |
| SCHEMBL20379869 | 0.79 | HTR6 (0.67) | CA1CA2CA9CA12CYP19A1 | |
| SCHEMBL7935644 | 0.79 | CA2 (0.67) | CA1CA2CA9CA12CYP19A1 | |
| SCHEMBL29032533 | 0.78 | CA1 (0.53) | CA1CA2CA9CA12CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0451007-B1 | Sulphonylphenyl-beta-D-thioxylosides, process for their preparation and their use in therapy | FOURNIER IND & SANTE (FR) | 1995-11-08 | — | — | EP | disclosed |
| EP-0451007-A1 | Sulphonylphenyl-beta-D-thioxylosides, process for their preparation and their use in therapy | FOURNIER INDUSTRIE ET SANTE (FR) | 1991-10-09 | — | — | EP | disclosed |