Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.51 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.51 |
| ▸ | DRD3 | P35462 | 1/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | HTT | P42858 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9177783 | 0.94 | CHRM2 (0.56) | CHRM2ADRA2BDRD3SIGMAR1HRH3 | |
| SCHEMBL24221611 | 0.86 | LMNA (0.48) | CHRM2ADRA2BDRD3SIGMAR1HRH3 | |
| SCHEMBL9325685 | 0.85 | PDPK1 (0.56) | CHRM2ADRA2BDRD3LMNAALDH1A1 | |
| SCHEMBL9405584 | 0.85 | PDPK1 (0.56) | CHRM2ADRA2BDRD3LMNAALDH1A1 | |
| SCHEMBL4558930 | 0.85 | SMN1; SMN2 (0.56) | ADRA2BLMNAALDH1A1SMN1; SMN2HTT | |
| SCHEMBL27162124 | 0.84 | HAO1 (0.45) | LMNAALDH1A1HTTCES2CES1 | |
| SCHEMBL9717258 | 0.81 | SMN1; SMN2 (0.51) | LMNAALDH1A1SMN1; SMN2HTTKDM4E | |
| SCHEMBL9190993 | 0.81 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2HTTKDM4ECES2 | |
| SCHEMBL9405579 | 0.81 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2HTTKDM4ECES2 | |
| SCHEMBL12955855 | 0.80 | KDM4E (0.48) | CHRM2ADRA2BDRD3SIGMAR1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0558157-B1 | Naphthalene compounds | MITSUBISHI GAS CHEMICAL CO (JP) | 1995-11-29 | — | — | EP | disclosed |
| EP-0390322-B1 | Naphthalene compounds | MITSUBISHI GAS CHEMICAL CO (JP) | 1994-04-27 | — | — | EP | disclosed |
| EP-0558157-A1 | Naphthalene compounds | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1993-09-01 | — | — | EP | disclosed |
| US-5151549-A | NAPHTHALENE COMPOUNDS | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1992-09-29 | — | — | US | disclosed |
| US-5146025-A | NAPHTHALENE COMPOUNDS | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1992-09-08 | — | — | US | disclosed |
| EP-0390322-A2 | Naphthalene compounds | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1990-10-03 | — | — | EP | disclosed |