Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.56 |
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.54 |
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | HTT | P42858 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.51 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | PGR | P06401 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9717258 | 0.95 | SMN1; SMN2 (0.51) | SMN1; SMN2MAPTL3MBTL1ALDH1A1LMNA | |
| SCHEMBL10489465 | 0.88 | PGR (0.58) | SMN1; SMN2MAPTL3MBTL1ALDH1A1LMNA | |
| SCHEMBL2128162 | 0.88 | PGR (0.58) | SMN1; SMN2MAPTL3MBTL1ALDH1A1LMNA | |
| SCHEMBL24221611 | 0.86 | LMNA (0.48) | MAPTALDH1A1LMNAHTTHSD17B10 | |
| SCHEMBL9405584 | 0.85 | PDPK1 (0.56) | SMN1; SMN2MAPTALDH1A1LMNAHSD17B10 | |
| SCHEMBL9325685 | 0.85 | PDPK1 (0.56) | SMN1; SMN2MAPTALDH1A1LMNAHSD17B10 | |
| SCHEMBL9192033 | 0.85 | CHRM2 (0.51) | SMN1; SMN2ALDH1A1LMNAHTTHPGD | |
| SCHEMBL4560389 | 0.84 | KMO (0.53) | SMN1; SMN2MAPTL3MBTL1PGRADRA2A | |
| SCHEMBL16186522 | 0.84 | SMN1; SMN2 (0.47) | SMN1; SMN2MAPTL3MBTL1ALDH1A1LMNA | |
| SCHEMBL27162124 | 0.84 | HAO1 (0.45) | ALDH1A1LMNAHTTHSD17B10RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090291988-A1 | Reversible Inhibitors of Monoamine Oxidase A and B | MERCK FROSST CANADA LTD. (CA) | 2009-11-26 | — | — | US | disclosed |
| JP-2000109439-A | PURIFICATION OF BIPHENYL-BASED OPTICALLY ACTIVE COMPOUND | ARAKAWA CHEM IND CO LTD | 2000-04-18 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090291988-A1 | Reversible Inhibitors of Monoamine Oxidase A and B | MAOB, MAOA, XDH | SMN1; SMN2 849/4885MAPT 1254/4885L3MBTL1 1098/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.