SCHEMBL919253

SCHEMBL919253

CC=C(CC)Oc1cc[c]cc1

nearest known ligand 0.32

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.32
ESR1 P03372 2/20 0.32
HIF1A Q16665 2/20 0.32
RECQL P46063 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
MEN1 O00255 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5519178 0.85 ESR1 (0.30) KMT2AESR1HIF1ARECQLSMN1; SMN2
SCHEMBL919397 0.78
SCHEMBL6273672 0.77
SCHEMBL920773 0.75
SCHEMBL17138151 0.73 ACHE (0.42) KMT2AMEN1
SCHEMBL4365235 0.73 KMT2A (0.32) KMT2AESR1HIF1ARECQLSMN1; SMN2
SCHEMBL128042 0.73 KMT2A (0.58) KMT2AESR1HIF1ARECQLSMN1; SMN2
SCHEMBL11032181 0.73 KMT2A (0.51) KMT2ASMN1; SMN2MEN1
SCHEMBL8011415 0.73 CHRNB2 (0.44) KMT2AESR1HIF1ARECQLSMN1; SMN2
SCHEMBL4365242 0.72 LMNA (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9115083-B2 Compounds from Antrodia cinnamomea and use thereof SIMPSON BIOTECH CO., LTD. (TW) 2015-08-25 US claimed
US-20140179753-A1 COMPOUNDS FROM ANTRODIA CINNAMOMEA AND USE THEREOF SIMPSON BIOTECH CO., LTD. (TW) 2014-06-26 US claimed
US-20130225649-A1 COMPOUNDS FROM ANTRODIA CINNAMOMEA AND USE THEREOF SIMPSON BIOTECH CO., LTD. (TW) 2013-08-29 US claimed
US-9115083-B2 Compounds from Antrodia cinnamomea and use thereof SIMPSON BIOTECH CO., LTD. (TW) 2015-08-25 US disclosed
US-20140179753-A1 COMPOUNDS FROM ANTRODIA CINNAMOMEA AND USE THEREOF SIMPSON BIOTECH CO., LTD. (TW) 2014-06-26 US disclosed
US-8703968-B2 Compounds from Antrodia cinnamomea and use thereof SIMPSON BIOTECH CO., LTD. (TW) 2014-04-22 US disclosed
US-20130225649-A1 COMPOUNDS FROM ANTRODIA CINNAMOMEA AND USE THEREOF SIMPSON BIOTECH CO., LTD. (TW) 2013-08-29 US disclosed
US-20110201649-A1 AGRICULTURAL COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-08-18 US disclosed
EP-2345328-A1 COMPOSITION FOR AGRICULTURAL USE Sumitomo Chemical Company, Limited (JP) 2011-07-20 EP disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130225649-A1 COMPOUNDS FROM ANTRODIA CINNAMOMEA AND USE THEREOF HAVCR2, CYP51A1, NPC1 KMT2A 3932/4885ESR1 1302/4885HIF1A 182/4885
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS WIZ, TST, NAT1 KMT2A 2469/4885ESR1 4697/4885HIF1A 2995/4885
US-20140179753-A1 COMPOUNDS FROM ANTRODIA CINNAMOMEA AND USE THEREOF HAVCR2, CYP51A1, NPC1 KMT2A 3932/4885ESR1 1302/4885HIF1A 182/4885
US-20110201649-A1 AGRICULTURAL COMPOSITION H1-0, H1-3, H1-2 KMT2A 1924/4885ESR1 2861/4885HIF1A 827/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.