Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 7/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 7/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.42 |
| ▸ | CXCL8 | P10145 | 2/20 | 0.42 |
| ▸ | RHEB | Q15382 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.39 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.35 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1692088 | 0.85 | SLC6A2 (0.39) | HTR1ASLC6A2SLC6A3CXCL8RHEB | |
| SCHEMBL919476 | 0.82 | LTA4H (0.41) | HTR1ASLC6A2SLC6A3SLC6A4ALDH1A1 | |
| SCHEMBL2333626 | 0.82 | SLC6A2 (0.38) | HTR1ASLC6A2SLC6A3CXCL8RHEB | |
| SCHEMBL30773497 | 0.80 | HTR1A (0.55) | HTR1ASLC6A2SLC6A3CXCL8RHEB | |
| SCHEMBL2389927 | 0.80 | HTR1A (0.55) | HTR1ASLC6A2SLC6A3CXCL8RHEB | |
| SCHEMBL8125840 | 0.79 | KEAP1 (0.38) | HTR1ASLC6A2RHEBSLC6A4ALDH1A1 | |
| SCHEMBL8441722 | 0.78 | ALDH1A1 (0.38) | HTR1ASLC6A2SLC6A3SLC6A4ALDH1A1 | |
| SCHEMBL6289414 | 0.78 | HTR1A (0.59) | HTR1ASLC6A2SLC6A3CXCL8RHEB | |
| SCHEMBL6293091 | 0.78 | HTR1A (0.59) | HTR1ASLC6A2SLC6A3CXCL8RHEB | |
| SCHEMBL6289399 | 0.78 | HTR1A (0.59) | HTR1ASLC6A2SLC6A3CXCL8RHEB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1044661-C | Pesticides, insecticides, miticides and nematocides compositions containing new silanes derivatives | HOECHST AG (DE) | 1999-08-18 | — | — | CN | disclosed |
| CN-1032005-C | Novel silane derivatives, formulations containing them and their use as pesticides | HOECHST AG (DE) | 1996-06-12 | — | — | CN | disclosed |
| CN-1027448-C | Heterocyclic neophenan analogs and their use as anti-inflammatory agents | HOECHST AG (DE) | 1995-01-18 | — | — | CN | disclosed |
| CN-1091425-A | Heterocyclic neophenan analogs, process for their preparation and their use as pesticides | HOECHST AG (DE) | 1994-08-31 | — | — | CN | disclosed |
| CN-1025502-C | Process for preparing silane derivatives | HOECHST AG (DE) | 1994-07-20 | — | — | CN | disclosed |
| CN-1025470-C | Pesticide, insecticide and acaricide compositions containing novel silane derivatives | HOECHST AG (DE) | 1994-07-20 | — | — | CN | disclosed |
| CN-1025501-C | Process for preparing silane derivatives | HOECHST AG (DE) | 1994-07-20 | — | — | CN | disclosed |
| CN-1077588-A | The agricultural chemicals, insecticide, the acaricidal nematicidal agent composition that contain novel silane derivs | HOECHST AG (DE) | 1993-10-27 | — | — | CN | disclosed |
| EP-0288810-B1 | HETEROCYCLIC NEOPHANE ANALOGS, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS PESTICIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-12-02 | — | — | EP | disclosed |
| US-5116826-A | SILAZANEOPHYL SULFIDES, AND THEIR USE AS PESTICIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-05-26 | — | — | US | disclosed |
| EP-0224024-B1 | SILANE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AGENTS CONTAINING THEM AND THEIR USE AS PESTICIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-06-20 | — | — | EP | disclosed |
| EP-0336199-A1 | Azaneophyl and silazaneophyl sulfides, process for their preparation, agents containing them, and their use as pesticides | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-10-11 | — | — | EP | disclosed |
| US-4864027-A | INSECTICIDES, NEMATOCIDES, MITICIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-09-05 | — | — | US | disclosed |
| EP-0288810-A1 | Heterocyclic neophane analogs, processes for their preparation and their use as pesticides | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-11-02 | — | — | EP | disclosed |
| CN-88102112-A | Heterocyclic neophenan analogs, process for their preparation and their use as pesticides | — | 1988-10-26 | — | — | CN | disclosed |
| US-4775664-A | INSECTICIDES, MITICIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-10-04 | — | — | US | disclosed |
| CN-87102981-A | Novel silane derivatives, process for their preparation, formulations containing them and their use as pesticides | — | 1988-03-02 | — | — | CN | disclosed |
| EP-0249015-A1 | Silane derivatives, process for their preparation, agents containing them, and their use as pesticides | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-12-16 | — | — | EP | disclosed |
| CN-86107292-A | Novel silane derivatives, process for their preparation, formulations containing them and their use as pesticides | — | 1987-07-29 | — | — | CN | disclosed |
| EP-0224024-A1 | Silane derivatives, process for their preparation, agents containing them and their use as pesticides | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-06-03 | — | — | EP | disclosed |