Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 16/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | PDE9A | O76083 | 1/20 | 0.32 |
| ▸ | PDE1A | P54750 | 1/20 | 0.32 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.32 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9190029 | 0.83 | ALDH1A1 (0.43) | HCAR2PDE1APDE1BPDE1C | |
| SCHEMBL6440045 | 0.81 | HCAR2 (0.43) | HCAR2RAB9A | |
| SCHEMBL9191469 | 0.79 | HCAR2 (0.47) | HCAR2RAB9APDE9APDE1APDE1B | |
| SCHEMBL9194026 | 0.78 | HCAR2 (0.44) | HCAR2RAB9A | |
| SCHEMBL3817859 | 0.78 | TNKS2 (0.44) | HCAR2 | |
| SCHEMBL9191276 | 0.76 | HCAR2 (0.51) | HCAR2RAB9A | |
| SCHEMBL9287657 | 0.76 | HCAR2 (0.47) | HCAR2RAB9APDE9APDE1APDE1B | |
| SCHEMBL9195100 | 0.75 | RAB9A (0.59) | HCAR2RAB9A | |
| SCHEMBL9191397 | 0.75 | ALDH1A1 (0.39) | HCAR2PDE1APDE1BPDE1C | |
| SCHEMBL9191459 | 0.74 | HCAR2 (0.40) | HCAR2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0399856-B1 | Pteridin-4 (3H)-ones, processes for their preparation and medicaments containing them | LIPHA (FR) | 1995-08-09 | — | — | EP | disclosed |
| US-5270465-A | 4(3H)-pteridinone compounds | LIPHA, LYONNAISE INDUSTRILLE PHARMACEUTIQUE (FR) | 1993-12-14 | — | — | US | disclosed |
| US-5167949-A | Antiallergic | LIPHA, LYONNAISE INDUSTRIELLE PHARMACEUTIQUE (FR) | 1992-12-01 | — | — | US | disclosed |
| EP-0399856-A1 | Pteridin-4 (3H)-ones, processes for their preparation and medicaments containing them | LIPHA, LYONNAISE INDUSTRIELLE PHARMACEUTIQUE (FR) | 1990-11-28 | — | — | EP | disclosed |