Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDE | P14735 | 3/20 | 0.52 |
| ▸ | MC4R | P32245 | 4/20 | 0.50 |
| ▸ | MC3R | P41968 | 3/20 | 0.50 |
| ▸ | FCER2 | P06734 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.46 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.46 |
| ▸ | ELANE | P08246 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9203772 | 0.86 | ITGB3 (0.54) | ITGB3ITGA2B | |
| SCHEMBL24597877 | 0.82 | CHRNA1 (0.51) | IDEFCER2ITGB3ITGA2B | |
| SCHEMBL9203094 | 0.82 | CHRND (0.54) | ITGB3ITGA2B | |
| SCHEMBL24597864 | 0.81 | CHRNA1 (0.54) | IDEFCER2 | |
| Hydrochloric Acid SCHEMBL9196037 | 0.81 | HPGDS (0.56) | — | |
| SCHEMBL9276580 | 0.80 | MC4R (0.48) | MC4RMC3RMEN1KMT2ANR1H4 | |
| SCHEMBL9276586 | 0.80 | MC4R (0.48) | MC4RMC3RMEN1KMT2ANR1H4 | |
| SCHEMBL8591091 | 0.80 | RAB9A (0.50) | IDEMEN1KMT2AL3MBTL1 | |
| SCHEMBL24597863 | 0.80 | IDE (0.45) | IDEFCER2ITGB3ITGA2B | |
| SCHEMBL9277061 | 0.79 | HTT (0.54) | NLRP3ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0680469-A1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | Dr. Karl Thomae GmbH (DE) | 1995-11-08 | — | — | EP | disclosed |
| WO-1994017035-A1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | DR. KARL THOMAE GMBH (DE) | 1994-08-04 | — | — | WO | disclosed |