Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRND | Q07001 | 10/20 | 0.54 |
| ▸ | CHRNA1 | P02708 | 6/20 | 0.54 |
| ▸ | CHRNG | P07510 | 6/20 | 0.54 |
| ▸ | CHRNB1 | P11230 | 6/20 | 0.54 |
| ▸ | GRIA1 | P42261 | 4/20 | 0.51 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.48 |
| ▸ | HPGDS | O60760 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9203772 | 0.87 | ITGB3 (0.54) | CHRNDCHRNA1CHRNGCHRNB1GRIA1 | |
| SCHEMBL9277061 | 0.85 | HTT (0.54) | CA2ITGB3ITGA2B | |
| SCHEMBL9195867 | 0.82 | IDE (0.52) | ITGB3ITGA2B | |
| SCHEMBL8528256 | 0.78 | CHRND (0.45) | CHRNDCHRNA1CHRNGCHRNB1GRIA1 | |
| SCHEMBL8524876 | 0.77 | ITGB3 (0.62) | CHRNDCHRNA1CHRNGCHRNB1GRIA1 | |
| SCHEMBL8524877 | 0.77 | ITGB3 (0.62) | CHRNDCHRNA1CHRNGCHRNB1GRIA1 | |
| SCHEMBL29868753 | 0.76 | LNPEP (0.55) | — | |
| SCHEMBL16728259 | 0.76 | CHRND (0.46) | CHRNDCHRNA1CHRNGCHRNB1GRIA1 | |
| SCHEMBL15186016 | 0.75 | CHRND (0.62) | CHRNDCHRNA1CHRNGCHRNB1GRIA1 | |
| SCHEMBL8269341 | 0.75 | ITGB3 (0.46) | CHRNDCHRNA1CHRNGCHRNB1GRIA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0680469-A1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | Dr. Karl Thomae GmbH (DE) | 1995-11-08 | — | — | EP | disclosed |
| WO-1994017035-A1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | DR. KARL THOMAE GMBH (DE) | 1994-08-04 | — | — | WO | disclosed |