SCHEMBL9190705

SCHEMBL9190705

Cc1ccc(F)cc1NC(=O)/C=C/C=C/C1(F)CC1c1ccc(Cl)c(Cl)c1

nearest known ligand 0.35

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.35
HTT P42858 2/20 0.35
CLCN2 P51788 1/20 0.34
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
HPGD P15428 2/20 0.33
MAPT P10636 4/20 0.33
KDM4E B2RXH2 3/20 0.33
MAPK1 P28482 2/20 0.33
GAA P10253 1/20 0.33
HSD17B10 Q99714 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
ABL1 P00519 1/20 0.33
IDH1 O75874 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
LMNA P02545 2/20 0.32
CYP2C19 P33261 1/20 0.32
HDAC1 Q13547 1/20 0.32
HDAC2 Q92769 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9188997 0.93 LMNA (0.36) ALDH1A1HTTMAPTKDM4EMAPK1
SCHEMBL9196803 0.89 MMP1 (0.40) ALDH1A1MAPTKDM4EGAALMNA
SCHEMBL9194823 0.87 MAPT (0.35) ALDH1A1HTTMEN1KMT2AHPGD
SCHEMBL9193927 0.84 LMNA (0.36) ALDH1A1HTTKMT2AMAPTKDM4E
SCHEMBL9196462 0.80 MMP1 (0.40) ALDH1A1HTTMEN1KMT2AHPGD
SCHEMBL9190700 0.79 ALDH1A1 (0.36) ALDH1A1HTTMEN1KMT2AMAPT
SCHEMBL9519053 0.77 NOS2 (0.34) NPSR1
SCHEMBL27399659 0.76 NPSR1 (0.40) HTTNPSR1
SCHEMBL9455335 0.76 MMP1 (0.36) ALDH1A1HPGDMAPTKDM4EGAA
SCHEMBL9190956 0.75 MMP1 (0.40) ALDH1A1HTTMEN1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0524041-B1 Pesticides ROUSSEL UCLAF (FR) 1995-09-20 EP claimed