Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ACACB | O00763 | 3/20 | 0.35 |
| ▸ | NOS1 | P29475 | 1/20 | 0.35 |
| ▸ | NOS2 | P35228 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.34 |
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9192118 | 0.86 | HCRTR1 (0.33) | L3MBTL1ACACBALDH1A1TDP1HCRTR1 | |
| SCHEMBL19664384 | 0.84 | KMT2A (0.45) | L3MBTL1LMNANOS1NOS2KMT2A | |
| SCHEMBL19664383 | 0.82 | ACACB (0.36) | L3MBTL1ACACBKMT2AMEN1NPC1 | |
| SCHEMBL9197151 | 0.80 | LMNA (0.41) | L3MBTL1LMNATSHRACACBKMT2A | |
| SCHEMBL9568958 | 0.77 | AAK1 (0.38) | ACACBNOS1NOS2KMT2AMEN1 | |
| SCHEMBL14342283 | 0.76 | L3MBTL1 (0.50) | L3MBTL1LMNATSHRKMT2AMEN1 | |
| SCHEMBL9199729 | 0.76 | ALDH1A1 (0.38) | L3MBTL1LMNATSHRACACBKMT2A | |
| SCHEMBL12150066 | 0.75 | CCNC (0.53) | LMNAKMT2AMEN1POLBNPC1 | |
| SCHEMBL19664382 | 0.73 | TDP1 (0.36) | L3MBTL1LMNAACACBKMT2AMEN1 | |
| SCHEMBL9663046 | 0.72 | TSHR (0.38) | LMNATSHRACACBNOS2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0278452-B1 | 2,4- and 2,5-Pyridine-dicarboxylic-acid derivatives, process for their preparation, their use and medicines based on these compounds | HOECHST AG (DE) | 1995-05-24 | — | — | EP | disclosed |
| EP-0278452-A2 | 2,4- and 2,5-Pyridine-dicarboxylic-acid derivatives, process for their preparation, their use and medicines based on these compounds | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-08-17 | — | — | EP | disclosed |