SCHEMBL919722

SCHEMBL919722

Fc1[c]cccc1OCc1ccco1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 3/20 0.44
ALDH1A1 P00352 4/20 0.38
MEN1 O00255 3/20 0.36
KMT2A Q03164 3/20 0.36
SGMS2 Q8NHU3 2/20 0.36
POLB P06746 3/20 0.35
TSHR P16473 2/20 0.35
KCNH3 Q9ULD8 1/20 0.34
GABRA1 P14867 1/20 0.34
GABRG2 P18507 1/20 0.34
GABRB3 P28472 1/20 0.34
GABRA5 P31644 1/20 0.34
GABRA3 P34903 1/20 0.34
GABRA2 P47869 1/20 0.34
HPGD P15428 3/20 0.33
MAPT P10636 2/20 0.33
CYP2D6 P10635 1/20 0.33
MAPK1 P28482 3/20 0.33
SLC1A3 P43003 1/20 0.33
SLC1A2 P43004 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL922375 0.74 TXNRD1 (0.37) ALDH1A1MEN1KMT2AGABRA1GABRG2
SCHEMBL920470 0.73 ALDH1A1 (0.50) ALDH1A1MEN1KMT2APOLBHPGD
SCHEMBL3211927 0.73 MAPT (0.50) GAAALDH1A1MAPTMAPK1LMNA
SCHEMBL920535 0.73 KDM4E (0.41) CYP2D6MAPK1KDM4E
SCHEMBL5759284 0.72 GAA (0.47) GAAALDH1A1MEN1KMT2ASGMS2
SCHEMBL921903 0.72 CDK4 (0.48) ALDH1A1SGMS2TSHRMAPTMAPK1
SCHEMBL921513 0.72 HTT (0.48) GAAALDH1A1KMT2APOLBTSHR
SCHEMBL920555 0.71 KDM4E (0.35) GAAMAPTCYP2D6MAPK1KDM4E
SCHEMBL920758 0.71 L3MBTL1 (0.40) GAAALDH1A1MEN1KMT2APOLB
SCHEMBL918931 0.71 KDM4E (0.39) GAAMEN1KMT2AMAPTCYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110201649-A1 AGRICULTURAL COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-08-18 US disclosed
EP-2345328-A1 COMPOSITION FOR AGRICULTURAL USE Sumitomo Chemical Company, Limited (JP) 2011-07-20 EP disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS WIZ, TST, NAT1 GAA 3332/4885ALDH1A1 2743/4885MEN1 4723/4885
US-20110201649-A1 AGRICULTURAL COMPOSITION H1-0, H1-3, H1-2 GAA 2649/4885ALDH1A1 4326/4885MEN1 1798/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.