SCHEMBL9197356

SCHEMBL9197356

COC(=O)c1ccc(-n2nc(C)cc2C)cc1S(N)(=O)=O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.48
POLB P06746 2/20 0.48
RXFP1 Q9HBX9 1/20 0.48
CA1 P00915 3/20 0.48
CA2 P00918 3/20 0.48
CA9 Q16790 3/20 0.48
CA5A P35218 1/20 0.48
ALDH1A1 P00352 4/20 0.47
L3MBTL1 Q9Y468 3/20 0.47
MAPT P10636 4/20 0.46
CA12 O43570 2/20 0.46
HPGD P15428 2/20 0.46
MYC P01106 1/20 0.44
TERT O14746 1/20 0.44
F10 P00742 3/20 0.43
TDP1 Q9NUW8 1/20 0.42
LMNA P02545 2/20 0.41
MAPK1 P28482 2/20 0.41
KMT2A Q03164 1/20 0.41
NPC1 O15118 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6786238 0.80 ALDH1A1 (0.54) SMN1; SMN2POLBALDH1A1L3MBTL1MAPT
SCHEMBL9193525 0.76 CA2 (0.51) CA1CA2CA9CA5AALDH1A1
SCHEMBL8811246 0.76 CA2 (0.57) POLBCA1CA2CA9CA5A
SCHEMBL22010624 0.74 CA2 (0.63) SMN1; SMN2POLBCA1CA2CA9
SCHEMBL6786036 0.73 SIRT6 (0.57) SMN1; SMN2POLBALDH1A1L3MBTL1MAPT
SCHEMBL8030650 0.72 GAA (0.67) SMN1; SMN2CA1CA2CA9CA5A
SCHEMBL5698738 0.71 PTGS2 (0.65) SMN1; SMN2POLBCA1CA2CA9
SCHEMBL11372105 0.71 CA1 (0.63) SMN1; SMN2CA1CA2CA9CA5A
SCHEMBL21962924 0.70 CA2 (0.61) SMN1; SMN2RXFP1CA1CA2CA9
SCHEMBL21962894 0.70 CA2 (0.61) SMN1; SMN2CA1CA2CA9CA5A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0382436-B1 N-substituted-3-(nitrogen-containing 5-membered ring)-benzenesulfonamide derivatives, preparation process thereof and herbicidal compositions KUREHA CHEMICAL IND CO LTD (JP) 1995-05-10 EP disclosed
US-5362885-A Herbicides KUREHA KAGAKU KOGYO K.K. (JP) 1994-11-08 US disclosed
US-5242894-A N-substituted-3-(nitrogen-containing 5-membered ring)-benzenesulfonamide derivatives, and herbicidal compositions KUREHA KAGAKU KOGYO K.K. (JP) 1993-09-07 US disclosed
US-5127937-A N-SUBSTITUTED-3-(NITROGEN-CONTAINING 5-MEMBERED RING)-BENZENESULFONAMIDE DERIVATIVES, AND HERBICIDAL COMPOSITIONS KUREHA KAGAKU KOGYO K.K. (JP) 1992-07-07 US disclosed
EP-0382436-A1 N-substituted-3-(nitrogen-containing 5-membered ring)-benzenesulfonamide derivatives, preparation process thereof and herbicidal compositions KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1990-08-16 EP disclosed