Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 5/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | MMP2 | P08253 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.50 |
| ▸ | GMNN | O75496 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | MMP9 | P14780 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | MMP8 | P22894 | 1/20 | 0.50 |
| ▸ | CCR1 | P32246 | 1/20 | 0.50 |
| ▸ | THPO | P40225 | 1/20 | 0.50 |
| ▸ | MTOR | P42345 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | MMP13 | P45452 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28263607 | 0.82 | ERN1 (0.46) | ALDH1A1LMNAKDM4EMMP2TSHR | |
| SCHEMBL69869 | 0.81 | ALDH1A1 (0.70) | ALDH1A1LMNAKDM4EMMP2TSHR | |
| SCHEMBL29906219 | 0.81 | ALDH1A1 (0.70) | ALDH1A1LMNAKDM4EMMP2TSHR | |
| SCHEMBL16040593 | 0.81 | ALDH1A1 (0.60) | ALDH1A1LMNAKDM4EMMP2TSHR | |
| SCHEMBL31057838 | 0.81 | ALDH1A1 (0.60) | ALDH1A1LMNAKDM4EMMP2TSHR | |
| SCHEMBL27908512 | 0.79 | ALDH1A1 (0.54) | ALDH1A1LMNAKDM4EMMP2TSHR | |
| SCHEMBL9197665 | 0.79 | ALDH1A1 (0.54) | ALDH1A1LMNAKDM4EMMP2TSHR | |
| SCHEMBL11430231 | 0.79 | LMNA (0.56) | ALDH1A1LMNAKDM4EMMP2TSHR | |
| SCHEMBL16383149 | 0.77 | ALDH1A1 (0.70) | ALDH1A1LMNAKDM4EMMP2TSHR | |
| SCHEMBL3756602 | 0.76 | SLC40A1 (0.52) | ALDH1A1LMNAKDM4EMMP2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8658801-B2 | Pesticides containing a bicyclic bisamide structure | SYNGENTA CROP PROTECTION, LLC (US) | 2014-02-25 | — | — | US | disclosed |
| US-8658801-B2 | Pesticides containing a bicyclic bisamide structure | SYNGENTA CROP PROTECTION, LLC (US) | 2014-02-25 | — | — | US | disclosed |
| US-8658801-B2 | Pesticides containing a bicyclic bisamide structure | SYNGENTA CROP PROTECTION, LLC (US) | 2014-02-25 | — | — | US | disclosed |
| CN-101426779-B | Pesticide containing bicyclic bisamide structure | SYNGENTA PARTICIPATIONS AG | 2013-08-21 | — | — | CN | disclosed |
| US-20090298816-A1 | PESTICIDES CONTAINING A BICYCLIC BISAMIDE STRUCTURE | SYNGENTA CROP PROTECTION, INC. (US) | 2009-12-03 | — | — | US | disclosed |
| US-20090298816-A1 | PESTICIDES CONTAINING A BICYCLIC BISAMIDE STRUCTURE | SYNGENTA CROP PROTECTION, INC. (US) | 2009-12-03 | — | — | US | disclosed |
| US-20090298816-A1 | PESTICIDES CONTAINING A BICYCLIC BISAMIDE STRUCTURE | SYNGENTA CROP PROTECTION, INC. (US) | 2009-12-03 | — | — | US | disclosed |
| EP-1984354-B1 | PESTICIDES CONTAINING A BICYCLIC BISAMIDE STRUCTURE | SYNGENTA PARTICIPATIONS AG (CH) | 2009-08-05 | — | — | EP | disclosed |
| EP-1984354-B1 | PESTICIDES CONTAINING A BICYCLIC BISAMIDE STRUCTURE | SYNGENTA PARTICIPATIONS AG (CH) | 2009-08-05 | — | — | EP | disclosed |
| CN-101426779-A | Pesticide containing bicyclic bisamide structure | SYNGENTA PARTICIPATIONS AG (CH) | 2009-05-06 | — | — | CN | disclosed |
| EP-1984354-A1 | PESTICIDES CONTAINING A BICYCLIC BISAMIDE STRUCTURE | Syngeta Participations AG (CH) | 2008-10-29 | — | — | EP | disclosed |
| WO-2007093402-A1 | PESTICIDES CONTAINING A BICYCLIC BISAMIDE STRUCTURE | SYNGENTA PARTICIPATIONS AG (CH) | 2007-08-23 | — | — | WO | disclosed |
| WO-2007093402-A1 | PESTICIDES CONTAINING A BICYCLIC BISAMIDE STRUCTURE | SYNGENTA PARTICIPATIONS AG (CH) | 2007-08-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090298816-A1 | PESTICIDES CONTAINING A BICYCLIC BISAMIDE STRUCTURE | DDT, ACHE, GAP43 | ALDH1A1 729/4885LMNA 534/4885KDM4E 2264/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.