Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | CCR1 | P32246 | 3/20 | 0.50 |
| ▸ | CCR5 | P51681 | 3/20 | 0.50 |
| ▸ | CCR8 | P51685 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | MMP2 | P08253 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | GMNN | O75496 | 1/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | MMP9 | P14780 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28189404 | 0.82 | LMNA (0.51) | LMNAALDH1A1KDM4ECCR1CCR5 | |
| SCHEMBL9945612 | 0.82 | LMNA (0.51) | LMNAALDH1A1KDM4ECCR1CCR5 | |
| SCHEMBL16040593 | 0.81 | ALDH1A1 (0.60) | LMNAALDH1A1KDM4ECCR1CCR5 | |
| SCHEMBL29906219 | 0.81 | ALDH1A1 (0.70) | LMNAALDH1A1KDM4ECCR1CCR5 | |
| SCHEMBL31057838 | 0.81 | ALDH1A1 (0.60) | LMNAALDH1A1KDM4ECCR1CCR5 | |
| SCHEMBL69869 | 0.81 | ALDH1A1 (0.70) | LMNAALDH1A1KDM4ECCR1CCR5 | |
| SCHEMBL9197665 | 0.79 | ALDH1A1 (0.54) | LMNAALDH1A1KDM4ECCR1CCR5 | |
| SCHEMBL27908512 | 0.79 | ALDH1A1 (0.54) | LMNAALDH1A1KDM4ECCR1CCR5 | |
| SCHEMBL4076198 | 0.79 | ALDH1A1 (0.54) | LMNAALDH1A1KDM4ECCR1CCR5 | |
| SCHEMBL3756602 | 0.79 | SLC40A1 (0.52) | LMNAALDH1A1KDM4ECCR1CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4186201-A | ANTIALLERGIC AGENTS | RIKER LABORATORIES, INC. (US) | 1980-01-29 | — | — | US | disclosed |
| US-4147694-A | ANTIALLERGENS, ANTIHISTAMINES | RIKER LABORATORIES, INC. (US) | 1979-04-03 | — | — | US | disclosed |