SCHEMBL9199353

SCHEMBL9199353

Cc1nn(C)c(S(N)(=O)=O)c1S(=O)(=O)N(C)C

nearest known ligand 0.36

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.36
NMT1 P30419 1/20 0.34
CA12 O43570 2/20 0.32
CA1 P00915 2/20 0.32
CA2 P00918 2/20 0.32
CA9 Q16790 2/20 0.32
CA4 P22748 1/20 0.32
CA6 P23280 1/20 0.32
CA5A P35218 1/20 0.32
CA7 P43166 1/20 0.32
CA14 Q9ULX7 1/20 0.32
CA5B Q9Y2D0 1/20 0.32
LMNA P02545 1/20 0.31
ABL1 P00519 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9202305 0.77 NMT1 (0.42) SMN1; SMN2NMT1CA12CA2CA9
SCHEMBL10204136 0.74 CA2 (0.37) SMN1; SMN2CA12CA1CA2CA9
SCHEMBL14295196 0.71 SMN1; SMN2 (0.40) SMN1; SMN2NMT1CA12CA2CA9
SCHEMBL9201775 0.71 KDM4E (0.43) SMN1; SMN2NMT1CA12CA1CA2
SCHEMBL1626536 0.71 L3MBTL1 (0.42) NMT1CA12CA1CA2CA9
SCHEMBL9199473 0.70 SMN1; SMN2 (0.33) SMN1; SMN2NMT1LMNATSHR
SCHEMBL3376273 0.70 TSHR (0.44) SMN1; SMN2NMT1CA12CA1CA2
SCHEMBL28327562 0.67 CA12 (0.35) NMT1CA12CA1CA2CA9
SCHEMBL9200671 0.67 KDM4E (0.37) SMN1; SMN2NMT1CA12CA1CA2
SCHEMBL9200106 0.67 ALDH1A1 (0.33) SMN1; SMN2CA12CA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0087780-B2 Pyrazolesulfonylurea derivative, preparation thereof, herbicide containing said derivative as active ingredient and herbicidal method by use thereof NISSAN CHEMICAL IND LTD (JP) 1995-02-15 EP disclosed
US-4954164-A Pyrazolesulfonylurea derivatives, preparation thereof, herbicide containing said derivative as active ingredient and herbicidal method by use thereof NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 1990-09-04 US disclosed
EP-0087780-A2 Pyrazolesulfonylurea derivative, preparation thereof, herbicide containing said derivative as active ingredient and herbicidal method by use thereof NISSAN CHEMICAL INDUSTRIES LTD. (JP) 1983-09-07 EP disclosed