Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | FEN1 | P39748 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | NQO1 | P15559 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9197378 | 0.90 | ICMT (0.33) | NQO1 | |
| SCHEMBL7439058 | 0.89 | MEN1 (0.34) | MEN1NPC1ALDH1A1RAB9AKMT2A | |
| SCHEMBL9286896 | 0.88 | ICMT (0.35) | MEN1NPC1ALDH1A1RAB9AKMT2A | |
| SCHEMBL7450971 | 0.85 | NQO1 (0.34) | FEN1HDAC3HDAC1HDAC2NQO1 | |
| SCHEMBL7435361 | 0.82 | MEN1 (0.35) | MEN1NPC1ALDH1A1RAB9AKMT2A | |
| SCHEMBL7483351 | 0.80 | ALDH1A1 (0.34) | MEN1ALDH1A1KMT2ANQO1CYP2C9 | |
| SCHEMBL9196771 | 0.80 | NQO1 (0.31) | NQO1 | |
| SCHEMBL7435888 | 0.79 | NQO1 (0.35) | MEN1NPC1ALDH1A1RAB9AKMT2A | |
| SCHEMBL7438652 | 0.79 | FEN1 (0.33) | MEN1NPC1ALDH1A1RAB9AKMT2A | |
| SCHEMBL7476430 | 0.78 | ICMT (0.36) | MEN1NPC1ALDH1A1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0668860-A1 | PYRAN-2-ONES AND 5,6-DIHYDROPYRAN-2-ONES USEFUL FOR TREATING HIV AND OTHER RETROVIRUSES | PHARMACIA & UPJOHN COMPANY (US) | 1995-08-30 | — | — | EP | disclosed |