SCHEMBL919974

SCHEMBL919974

Nc1ccc(C(=O)NCc2cccc(Oc3ccccc3)c2)c(N)n1

nearest known ligand 0.53

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 0.53
KDM4E B2RXH2 1/20 0.53
USP2 O75604 1/20 0.53
ALDH1A1 P00352 1/20 0.53
FFAR1 O14842 4/20 0.52
MAPK14 Q16539 2/20 0.50
PPARG P37231 2/20 0.48
PPARA Q07869 2/20 0.48
RAB9A P51151 1/20 0.48
MAPK8 P45983 1/20 0.48
PLAU P00749 1/20 0.48
PPARD Q03181 1/20 0.47
CA2 P00918 1/20 0.47
CA4 P22748 1/20 0.47
ADORA2A P29274 1/20 0.47
ADORA1 P30542 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL922515 0.89 HPGD (0.53) HPGDALDH1A1MAPK14PPARGPPARA
SCHEMBL920375 0.89 MAPK14 (0.51) HPGDKDM4EUSP2ALDH1A1FFAR1
SCHEMBL920750 0.89 KDM4E (0.54) HPGDKDM4EUSP2ALDH1A1FFAR1
SCHEMBL920645 0.85 KDM4E (0.53) HPGDKDM4EUSP2ALDH1A1FFAR1
SCHEMBL1680406 0.84 MAPK8 (0.63) HPGDKDM4EUSP2ALDH1A1FFAR1
SCHEMBL921580 0.82 MMP13 (0.58) HPGDKDM4EUSP2ALDH1A1MAPK14
SCHEMBL919388 0.82 MAPK14 (0.47) HPGDKDM4EUSP2ALDH1A1FFAR1
SCHEMBL920568 0.81 MMP13 (0.57) HPGDKDM4EUSP2ALDH1A1PPARG
SCHEMBL922174 0.81 KDM4E (0.53) HPGDKDM4EUSP2ALDH1A1PPARG
SCHEMBL921456 0.81 KDM4E (0.47) HPGDKDM4EUSP2ALDH1A1FFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed
WO-2009107764-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS 住友化学株式会社 (JP) 2009-09-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS WIZ, TST, NAT1 HPGD 1273/4885KDM4E 3657/4885USP2 3233/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.