Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 3/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | BCHE | P06276 | 2/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9201209 | 0.84 | MAPT (0.32) | MAPTRECQL | |
| SCHEMBL9198647 | 0.80 | ACHE (0.37) | MAPTRECQLKMT2ASMN1; SMN2NPC1 | |
| SCHEMBL9199236 | 0.80 | MAPT (0.39) | MAPTRECQLMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9196782 | 0.78 | MAPT (0.38) | GPR35MAPTRECQLMEN1KMT2A | |
| SCHEMBL9199383 | 0.76 | HPGD (0.47) | MAPTRECQLMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9205543 | 0.75 | ALDH1A1 (0.39) | MAPTRECQLMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9207049 | 0.74 | GAA (0.36) | MAPTRECQLMEN1CYP3A4KMT2A | |
| SCHEMBL9197282 | 0.72 | SLC6A3 (0.42) | MAPTMEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL9200578 | 0.72 | HPGD (0.49) | MAPTRECQLMEN1KMT2ACYP1A2 | |
| SCHEMBL9201424 | 0.72 | LMNA (0.49) | MAPTRECQLMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0497816-B1 | TREATMENT OF HIV INFECTIONS AND COMPOUNDS USEFUL THEREIN | UNIROYAL CHEMICAL LTD (CA) | 1995-05-17 | — | — | EP | claimed |