Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 5/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | BCL2 | P10415 | 1/20 | 0.34 |
| ▸ | THRA | P10827 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9200578 | 0.86 | HPGD (0.49) | MAPTRECQLGAAHTTLMNA | |
| SCHEMBL9196782 | 0.85 | MAPT (0.38) | MAPTRECQLGAALMNANPC1 | |
| SCHEMBL9207049 | 0.83 | GAA (0.36) | MAPTRECQLGAAHTTLMNA | |
| SCHEMBL9199383 | 0.83 | HPGD (0.47) | MAPTRECQLGAAHTTLMNA | |
| SCHEMBL9205543 | 0.82 | ALDH1A1 (0.39) | MAPTRECQLGAAHTTLMNA | |
| SCHEMBL9206016 | 0.80 | MEN1 (0.40) | NPC1RAB9AALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL9199834 | 0.80 | GPR35 (0.38) | MAPTRECQLHTTLMNANPC1 | |
| SCHEMBL9198647 | 0.80 | ACHE (0.37) | MAPTRECQLGAAHTTLMNA | |
| SCHEMBL9206141 | 0.78 | MAPT (0.58) | MAPTRECQLGAALMNANPC1 | |
| SCHEMBL9201424 | 0.78 | LMNA (0.49) | MAPTRECQLGAAHTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0497816-B1 | TREATMENT OF HIV INFECTIONS AND COMPOUNDS USEFUL THEREIN | UNIROYAL CHEMICAL LTD (CA) | 1995-05-17 | — | — | EP | claimed |