Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | PPID | Q08752 | 1/20 | 0.40 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | RORA | P35398 | 1/20 | 0.37 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 2/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7854590 | 0.78 | TDP1 (0.47) | MMP8ALDH1A1L3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL7861325 | 0.78 | L3MBTL1 (0.57) | ALDH1A1L3MBTL1LMNASMN1; SMN2NPC1 | |
| SCHEMBL9204703 | 0.75 | L3MBTL1 (0.54) | ALDH1A1L3MBTL1LMNAPIN1MEN1 | |
| SCHEMBL9205212 | 0.75 | ALDH1A1 (0.50) | MMP8ALDH1A1L3MBTL1LMNAPIN1 | |
| SCHEMBL628126 | 0.75 | KMT2A (0.53) | LMNAPIN1SMN1; SMN2MEN1NPC1 | |
| SCHEMBL7323723 | 0.74 | TDP1 (0.56) | MMP8ALDH1A1L3MBTL1PIN1MEN1 | |
| SCHEMBL9199837 | 0.73 | ALDH1A1 (0.47) | MMP8ALDH1A1RECQLL3MBTL1LMNA | |
| Water SCHEMBL27325173 | 0.72 | TDP1 (0.51) | MMP8ALDH1A1RECQLL3MBTL1LMNA | |
| SCHEMBL3228799 | 0.72 | KMT2A (0.57) | MMP8L3MBTL1LMNAPIN1SMN1; SMN2 | |
| SCHEMBL14026722 | 0.72 | KMT2A (0.41) | MMP8ALDH1A1L3MBTL1LMNAPIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0423802-B1 | Phenoxy-heterocyclic compounds | MERRELL DOW PHARMA (US) | 1995-08-09 | — | — | EP | disclosed |
| US-5134154-A | Phenoxy-heterocyclic compounds | MERRELL DOW PHARMACEUTICALS INC. (US) | 1992-07-28 | — | — | US | disclosed |
| EP-0423802-A1 | Phenoxy-heterocyclic compounds | MERRELL DOW PHARMACEUTICALS INC. (US) | 1991-04-24 | — | — | EP | disclosed |