Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | MMP8 | P22894 | 2/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | PPID | Q08752 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | NR5A1 | Q13285 | 2/20 | 0.39 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | PTPRB | P23467 | 1/20 | 0.39 |
| ▸ | ACP1 | P24666 | 1/20 | 0.39 |
| ▸ | RORA | P35398 | 1/20 | 0.39 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7861235 | 0.83 | ALDH1A1 (0.48) | ALDH1A1MMP8RECQLKDM4ELMNA | |
| SCHEMBL7860078 | 0.82 | ALDH1A1 (0.47) | ALDH1A1MMP8RECQLL3MBTL1PIN1 | |
| SCHEMBL9206341 | 0.77 | KMT2A (0.48) | ALDH1A1MMP8RECQLKDM4ELMNA | |
| SCHEMBL7431853 | 0.76 | ALDH1A1 (0.57) | ALDH1A1MMP8RECQLLMNAL3MBTL1 | |
| SCHEMBL16865453 | 0.76 | ALDH1A1 (0.57) | ALDH1A1MMP8RECQLLMNAL3MBTL1 | |
| SCHEMBL20350605 | 0.74 | MMP8 (0.58) | ALDH1A1MMP8RECQLLMNAL3MBTL1 | |
| SCHEMBL9205410 | 0.73 | PPARG (0.50) | ALDH1A1MMP8KDM4ELMNATDP1 | |
| SCHEMBL22216571 | 0.73 | ALDH1A1 (0.48) | ALDH1A1MMP8RECQLLMNATDP1 | |
| SCHEMBL9199846 | 0.73 | MMP8 (0.45) | ALDH1A1MMP8RECQLKDM4ELMNA | |
| SCHEMBL6740786 | 0.72 | ALDH1A1 (0.56) | ALDH1A1MMP8RECQLLMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0423802-B1 | Phenoxy-heterocyclic compounds | MERRELL DOW PHARMA (US) | 1995-08-09 | — | — | EP | disclosed |
| US-5134154-A | Phenoxy-heterocyclic compounds | MERRELL DOW PHARMACEUTICALS INC. (US) | 1992-07-28 | — | — | US | disclosed |
| EP-0423802-A1 | Phenoxy-heterocyclic compounds | MERRELL DOW PHARMACEUTICALS INC. (US) | 1991-04-24 | — | — | EP | disclosed |