Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.36 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | FABP4 | P15090 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9206193 | 0.84 | AGTR1 (0.33) | AGTR1AGTR2HPGD | |
| SCHEMBL9199463 | 0.83 | PLA2G2A (0.36) | AGTR1AGTR2 | |
| SCHEMBL9196516 | 0.82 | MRGPRX4 (0.38) | AGTR1AGTR2FABP4 | |
| SCHEMBL9203204 | 0.81 | PLA2G2A (0.35) | AGTR1AGTR2 | |
| SCHEMBL9199466 | 0.78 | NR4A2 (0.41) | — | |
| SCHEMBL9196521 | 0.78 | HDAC8 (0.39) | AGTR1AGTR2TDP1 | |
| SCHEMBL9207021 | 0.72 | MAPT (0.32) | AGTR1AGTR2 | |
| SCHEMBL9197935 | 0.71 | CPB1 (0.31) | AGTR1AGTR2 | |
| SCHEMBL9197943 | 0.69 | AGTR1 (0.33) | TP53AGTR1AGTR2ALDH1A1NPSR1 | |
| SCHEMBL9287158 | 0.69 | TLR7 (0.39) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0517812-A4 | ANGIOTENSIN II ANTAGONISTS INCORPORATING A SUBSTITUTED BENZYL ELEMENT | MERCK & CO INC (US) | 1995-10-18 | — | — | EP | disclosed |
| EP-0517812-A1 | ANGIOTENSIN II ANTAGONISTS INCORPORATING A SUBSTITUTED BENZYL ELEMENT | MERCK & CO. INC. (US) | 1992-12-16 | — | — | EP | disclosed |