Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 2/20 | 0.36 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.35 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9196516 | 0.91 | MRGPRX4 (0.38) | PLA2G2AAGTR1AGTR2 | |
| SCHEMBL9203204 | 0.90 | PLA2G2A (0.35) | PLA2G2AAGTR1AGTR2MAPTOPRM1 | |
| SCHEMBL9199466 | 0.84 | NR4A2 (0.41) | — | |
| SCHEMBL9207021 | 0.84 | MAPT (0.32) | AGTR1AGTR2MAPT | |
| SCHEMBL9200319 | 0.83 | TP53 (0.37) | AGTR1AGTR2 | |
| SCHEMBL9196521 | 0.82 | HDAC8 (0.39) | AGTR1AGTR2MAPT | |
| SCHEMBL9204518 | 0.78 | — | — | |
| SCHEMBL9197935 | 0.78 | CPB1 (0.31) | AGTR1AGTR2MAPT | |
| SCHEMBL9197943 | 0.73 | AGTR1 (0.33) | AGTR1AGTR2MAPT | |
| SCHEMBL9203002 | 0.73 | PPARG (0.47) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0517812-A4 | ANGIOTENSIN II ANTAGONISTS INCORPORATING A SUBSTITUTED BENZYL ELEMENT | MERCK & CO INC (US) | 1995-10-18 | — | — | EP | disclosed |
| EP-0517812-A1 | ANGIOTENSIN II ANTAGONISTS INCORPORATING A SUBSTITUTED BENZYL ELEMENT | MERCK & CO. INC. (US) | 1992-12-16 | — | — | EP | disclosed |