SCHEMBL920122

SCHEMBL920122

Cc1ccc(CNC(=O)c2cccnc2N)cc1

nearest known ligand 0.68

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
HPGD P15428 5/20 0.68
ALDH1A1 P00352 4/20 0.66
KDM4E B2RXH2 2/20 0.66
CYP1A2 P05177 1/20 0.60
CYP3A4 P08684 1/20 0.60
CYP2C9 P11712 1/20 0.60
CYP2C19 P33261 1/20 0.60
POLB P06746 1/20 0.56
SMN1; SMN2 Q16637 3/20 0.54
L3MBTL1 Q9Y468 2/20 0.54
KMT2A Q03164 2/20 0.53
HSD17B10 Q99714 1/20 0.52
MAPK1 P28482 1/20 0.51
NSD2 O96028 1/20 0.51
LMNA P02545 1/20 0.51
PRKCI P41743 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL922484 0.93 HPGD (0.62) HPGDALDH1A1KDM4ECYP1A2CYP3A4
SCHEMBL922511 0.91 HPGD (0.60) HPGDALDH1A1KDM4ECYP1A2CYP3A4
SCHEMBL921161 0.89 HPGD (0.56) HPGDALDH1A1KDM4ECYP1A2CYP3A4
SCHEMBL921272 0.87 MT-CO2 (0.54) HPGDALDH1A1KDM4ESMN1; SMN2KMT2A
SCHEMBL27824616 0.87 NSD2 (0.56) HPGDALDH1A1KDM4ESMN1; SMN2KMT2A
SCHEMBL922492 0.87 NSD2 (0.66) HPGDL3MBTL1KMT2AMAPK1NSD2
SCHEMBL922505 0.86 HPGD (0.54) HPGDALDH1A1KDM4ECYP1A2CYP3A4
SCHEMBL923044 0.86 KMT2A (0.70) HPGDCYP1A2CYP2C19L3MBTL1KMT2A
SCHEMBL18715195 0.86 HPGD (0.71) HPGDALDH1A1KDM4ECYP1A2CYP3A4
SCHEMBL921981 0.85 HPGD (0.70) HPGDALDH1A1POLBSMN1; SMN2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS WIZ, TST, NAT1 HPGD 1273/4885ALDH1A1 2743/4885KDM4E 3657/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.