SCHEMBL921161

SCHEMBL921161

CCc1ccc(CNC(=O)c2cccnc2N)cc1

nearest known ligand 0.56

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HPGD P15428 4/20 0.56
LMNA P02545 2/20 0.54
SMN1; SMN2 Q16637 1/20 0.54
KMT2A Q03164 1/20 0.52
KDM4E B2RXH2 1/20 0.51
ALDH1A1 P00352 1/20 0.51
NSD2 O96028 1/20 0.51
PRKCI P41743 2/20 0.50
VCP P55072 1/20 0.49
MAPK8 P45983 1/20 0.49
ATM Q13315 1/20 0.49
CYP1A2 P05177 1/20 0.48
CYP3A4 P08684 1/20 0.48
CYP2C9 P11712 1/20 0.48
CYP2C19 P33261 1/20 0.48
HDAC6 Q9UBN7 1/20 0.48
MAPK1 P28482 1/20 0.48
APEX1 P27695 1/20 0.48
NAPRT Q6XQN6 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL920473 0.93 HPGD (0.57) HPGDLMNASMN1; SMN2KMT2AALDH1A1
SCHEMBL922505 0.89 HPGD (0.54) HPGDLMNASMN1; SMN2KMT2AKDM4E
SCHEMBL920122 0.89 HPGD (0.68) HPGDLMNASMN1; SMN2KMT2AKDM4E
SCHEMBL920245 0.88 HPGD (0.54) HPGDLMNASMN1; SMN2KMT2AKDM4E
SCHEMBL921272 0.87 MT-CO2 (0.54) HPGDLMNASMN1; SMN2KMT2AKDM4E
SCHEMBL27824616 0.87 NSD2 (0.56) HPGDLMNASMN1; SMN2KMT2AKDM4E
SCHEMBL922492 0.87 NSD2 (0.66) HPGDLMNAKMT2ANSD2PRKCI
SCHEMBL921173 0.87 KDR (0.53) HPGDLMNASMN1; SMN2KMT2AKDM4E
SCHEMBL920353 0.87 LMNA (0.65) HPGDLMNASMN1; SMN2KMT2AKDM4E
SCHEMBL923044 0.86 KMT2A (0.70) HPGDLMNAKMT2ANSD2CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101951771-A Composition for agricultural use for controlling or preventing plant diseases caused by plant pathogens SUMITOMO CHEMICAL CO 2011-01-19 CN disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS WIZ, TST, NAT1 HPGD 1273/4885LMNA 4812/4885SMN1; SMN2 4796/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.