SCHEMBL920156

SCHEMBL920156

Nc1ncccc1C(=O)NCc1ccc(Oc2cc(Cl)cc(Cl)c2)cc1

nearest known ligand 0.55

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CARM1 Q86X55 1/20 0.53
PRMT6 Q96LA8 1/20 0.53
MAPK8 P45983 2/20 0.52
ALDH1A1 P00352 2/20 0.50
HPGD P15428 3/20 0.49
GAA P10253 1/20 0.49
HTT P42858 1/20 0.49
ATM Q13315 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
LMNA P02545 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
CYP3A4 P08684 1/20 0.47
MAPK14 Q16539 1/20 0.47
EGLN1 Q9GZT9 1/20 0.47
POLB P06746 1/20 0.45
KLKB1 P03952 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL922025 0.92 ALDH1A1 (0.58) MAPK8ALDH1A1HPGDGAAHTT
SCHEMBL920561 0.91 MAPK8 (0.53) MAPK8ALDH1A1HPGDGAAHTT
SCHEMBL919626 0.88 MAPK8 (0.49) MAPK8ALDH1A1HPGDGAAHTT
SCHEMBL920002 0.88 MAPK8 (0.51) MAPK8ALDH1A1HPGDGAAHTT
SCHEMBL920612 0.87 MAPK8 (0.48) MAPK8ALDH1A1HPGDGAAHTT
SCHEMBL920461 0.87 MAPK8 (0.67) MAPK8ALDH1A1HPGDGAAHTT
SCHEMBL922349 0.87 HPGD (0.53) MAPK8ALDH1A1HPGDGAAHTT
SCHEMBL920265 0.85 MAPK8 (0.55) MAPK8ALDH1A1HPGDHTTLMNA
SCHEMBL921037 0.85 HPGD (0.66) MAPK8ALDH1A1HPGDLMNASMN1; SMN2
SCHEMBL920343 0.85 KMT2A (0.61) MAPK8HPGDL3MBTL1LMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS WIZ, TST, NAT1 CARM1 273/4885PRMT6 1994/4885MAPK8 2313/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.