Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 3/20 | 0.38 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.37 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.34 |
| ▸ | PTGES | O14684 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9202319 | 0.92 | SLC1A5 (0.37) | TRPM8SLC1A5NR1H3KMT2ACTBP2 | |
| SCHEMBL9194668 | 0.91 | TDP1 (0.39) | NR1H3TAS2R14KMT2AMEN1TDP1 | |
| SCHEMBL9199475 | 0.89 | KMT2A (0.36) | TRPM8KMT2AMEN1CTBP2 | |
| SCHEMBL9201326 | 0.87 | ALDH1A1 (0.37) | NR1H3KMT2AMEN1TDP1 | |
| SCHEMBL9195755 | 0.87 | ALDH1A1 (0.37) | NR1H3KMT2AMEN1 | |
| SCHEMBL9195772 | 0.84 | EPHX1 (0.38) | TAS2R14KMT2AMEN1TDP1CHRM1 | |
| SCHEMBL9198354 | 0.84 | KMT2A (0.32) | KMT2AMEN1TDP1 | |
| SCHEMBL9203185 | 0.83 | TDP1 (0.34) | KMT2AMEN1TDP1 | |
| SCHEMBL9196838 | 0.83 | TDP1 (0.37) | KMT2AMEN1TDP1 | |
| SCHEMBL9194700 | 0.82 | KMT2A (0.38) | NR1H3KMT2AMEN1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0680469-A1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | Dr. Karl Thomae GmbH (DE) | 1995-11-08 | — | — | EP | disclosed |
| WO-1994017035-A1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | DR. KARL THOMAE GMBH (DE) | 1994-08-04 | — | — | WO | disclosed |