SCHEMBL920164

SCHEMBL920164

Fc1[c]cccc1OCc1cccc(Cl)c1

nearest known ligand 0.52

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ENPP2 Q13822 1/20 0.52
SLC6A4 P31645 1/20 0.50
MAOB P27338 3/20 0.49
CYP3A4 P08684 2/20 0.49
IDO1 P14902 2/20 0.49
AGXT P21549 2/20 0.49
CARM1 Q86X55 2/20 0.46
PRMT1 Q99873 2/20 0.46
HTR6 P50406 1/20 0.46
DHFR P00374 1/20 0.46
DCPS Q96C86 1/20 0.46
ADRA1D P25100 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL921216 0.85 IDO1 (0.51) MAOBCYP3A4IDO1AGXTHTR6
SCHEMBL921988 0.83 MAPT (0.46) SLC6A4MAOBCYP3A4IDO1AGXT
SCHEMBL920331 0.82 IDO1 (0.49) MAOBIDO1HTR6ADRA1D
SCHEMBL3211927 0.81 MAPT (0.50) SLC6A4ADRA1D
SCHEMBL921931 0.80 ABCB1 (0.56) MAOBIDO1AGXTADRA1D
SCHEMBL921311 0.79 MRGPRX4 (0.53) SLC6A4MAOBHTR6
SCHEMBL919103 0.78 DHFR (0.45) SLC6A4MAOBIDO1AGXTHTR6
SCHEMBL920470 0.78 ALDH1A1 (0.50) SLC6A4MAOBIDO1AGXT
SCHEMBL921724 0.74 SMN1; SMN2 (0.50) CYP3A4
SCHEMBL2454031 0.74 MAOB (0.50) ENPP2MAOBCYP3A4IDO1AGXT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110201649-A1 AGRICULTURAL COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-08-18 US disclosed
EP-2345328-A1 COMPOSITION FOR AGRICULTURAL USE Sumitomo Chemical Company, Limited (JP) 2011-07-20 EP disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS WIZ, TST, NAT1 ENPP2 4504/4885SLC6A4 2590/4885MAOB 3730/4885
US-20110201649-A1 AGRICULTURAL COMPOSITION H1-0, H1-3, H1-2 ENPP2 4359/4885SLC6A4 3323/4885MAOB 4351/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.