SCHEMBL919103

SCHEMBL919103

Fc1cc(F)cc(COc2ccc[c]c2F)c1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DHFR P00374 1/20 0.45
DCPS Q96C86 1/20 0.45
IDO1 P14902 3/20 0.43
LMNA P02545 4/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
ALDH1A1 P00352 2/20 0.38
PKM P14618 1/20 0.38
KDM1A O60341 1/20 0.37
MAOB P27338 2/20 0.36
MAPT P10636 2/20 0.36
KDM4E B2RXH2 1/20 0.36
PLA2G1B P04054 1/20 0.36
GAA P10253 1/20 0.36
ATG4B Q9Y4P1 1/20 0.36
KMT2A Q03164 3/20 0.36
MEN1 O00255 2/20 0.36
HTR6 P50406 1/20 0.36
RAB9A P51151 2/20 0.36
NPC1 O15118 1/20 0.36
HTR1A P08908 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL921216 0.87 IDO1 (0.51) IDO1LMNAL3MBTL1ALDH1A1MAOB
SCHEMBL920470 0.86 ALDH1A1 (0.50) IDO1LMNAALDH1A1PKMMAOB
SCHEMBL3211927 0.83 MAPT (0.50) LMNAL3MBTL1ALDH1A1PKMKDM1A
SCHEMBL921988 0.79 MAPT (0.46) IDO1LMNAL3MBTL1MAOBMAPT
SCHEMBL920040 0.79 KMT2A (0.44) LMNAL3MBTL1ALDH1A1PKMMAOB
SCHEMBL921724 0.79 SMN1; SMN2 (0.50) LMNAALDH1A1PKMMAPTKMT2A
SCHEMBL920331 0.78 IDO1 (0.49) IDO1L3MBTL1MAOBMAPTHTR6
SCHEMBL920164 0.78 ENPP2 (0.52) DHFRDCPSIDO1MAOBHTR6
SCHEMBL922375 0.76 TXNRD1 (0.37) L3MBTL1ALDH1A1PKMMAPTKMT2A
SCHEMBL921811 0.76 PARP15 (0.36) ALDH1A1PKMKMT2AMEN1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110201649-A1 AGRICULTURAL COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-08-18 US disclosed
EP-2345328-A1 COMPOSITION FOR AGRICULTURAL USE Sumitomo Chemical Company, Limited (JP) 2011-07-20 EP disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS WIZ, TST, NAT1 DHFR 1140/4885DCPS 1956/4885IDO1 675/4885
US-20110201649-A1 AGRICULTURAL COMPOSITION H1-0, H1-3, H1-2 DHFR 2892/4885DCPS 3942/4885IDO1 236/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.