Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 5/20 | 0.47 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.44 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9203008 | 0.86 | AGTR1 (0.46) | PPARGAGTR1AGTR2 | |
| SCHEMBL9530606 | 0.80 | AGTR1 (0.51) | AGTR1AGTR2 | |
| SCHEMBL9044726 | 0.75 | AGTR1 (0.51) | AGTR1AGTR2 | |
| SCHEMBL9196516 | 0.74 | MRGPRX4 (0.38) | AGTR1AGTR2 | |
| SCHEMBL9199463 | 0.73 | PLA2G2A (0.36) | AGTR1AGTR2 | |
| SCHEMBL9039836 | 0.73 | AGTR1 (0.51) | AGTR1AGTR2 | |
| SCHEMBL812 | 0.73 | AGTR1 (0.60) | AGTR1AGTR2 | |
| SCHEMBL9195831 | 0.72 | AGTR2 (0.46) | PPARGAGTR2 | |
| SCHEMBL9041908 | 0.72 | PDE4A (0.52) | AGTR1AGTR2 | |
| SCHEMBL9203204 | 0.71 | PLA2G2A (0.35) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0517812-A4 | ANGIOTENSIN II ANTAGONISTS INCORPORATING A SUBSTITUTED BENZYL ELEMENT | MERCK & CO INC (US) | 1995-10-18 | — | — | EP | disclosed |
| EP-0517812-A1 | ANGIOTENSIN II ANTAGONISTS INCORPORATING A SUBSTITUTED BENZYL ELEMENT | MERCK & CO. INC. (US) | 1992-12-16 | — | — | EP | disclosed |