SCHEMBL920443

SCHEMBL920443

Cc1cccc(COc2cc[c]c(F)c2)c1

nearest known ligand 0.57

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MAOB P27338 13/20 0.57
MAOA P21397 3/20 0.52
IDO1 P14902 2/20 0.46
ACHE P22303 1/20 0.46
NR1H4 Q96RI1 2/20 0.44
AR P10275 1/20 0.44
GRM5 P41594 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL921277 0.85 MAOB (0.59) MAOBMAOAIDO1
SCHEMBL920733 0.84 MAOB (0.62) MAOBIDO1ACHE
SCHEMBL920605 0.83 MAOB (0.51) MAOBMAOAACHEAR
SCHEMBL920621 0.83 ALOX5 (0.51) MAOBMAOA
SCHEMBL921872 0.82 MAOB (0.54) MAOBMAOAIDO1
SCHEMBL920280 0.80 MAOB (0.61) MAOBMAOAIDO1ACHENR1H4
SCHEMBL920508 0.79 FFAR1 (0.50) MAOBMAOAGRM5
SCHEMBL15344203 0.79 MAOB (0.80) MAOBMAOAIDO1ACHENR1H4
SCHEMBL16808963 0.78 MAOB (0.69) MAOBMAOA
SCHEMBL13723329 0.77 MAOB (0.47) MAOBMAOAIDO1ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110201649-A1 AGRICULTURAL COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-08-18 US disclosed
EP-2345328-A1 COMPOSITION FOR AGRICULTURAL USE Sumitomo Chemical Company, Limited (JP) 2011-07-20 EP disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS WIZ, TST, NAT1 MAOB 3730/4885MAOA 3447/4885IDO1 675/4885
US-20110201649-A1 AGRICULTURAL COMPOSITION H1-0, H1-3, H1-2 MAOB 4351/4885MAOA 4535/4885IDO1 236/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.