SCHEMBL920733

SCHEMBL920733

COc1cccc(COc2cc[c]c(F)c2)c1

nearest known ligand 0.62

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MAOB P27338 12/20 0.62
IDO1 P14902 2/20 0.50
AGXT P21549 2/20 0.50
MRGPRX4 Q96LA9 1/20 0.50
APP P05067 1/20 0.49
NPC1 O15118 1/20 0.48
RAB9A P51151 1/20 0.48
BCHE P06276 1/20 0.47
ABCB1 P08183 1/20 0.47
HTR1A P08908 1/20 0.47
DRD2 P14416 1/20 0.47
ACHE P22303 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL920443 0.84 MAOB (0.57) MAOBIDO1ACHE
SCHEMBL921277 0.84 MAOB (0.59) MAOBIDO1AGXT
SCHEMBL920022 0.84 MAOB (0.53) MAOBAPPNPC1RAB9A
SCHEMBL920621 0.82 ALOX5 (0.51) MAOBRAB9ABCHE
SCHEMBL921872 0.81 MAOB (0.54) MAOBIDO1AGXT
SCHEMBL920589 0.80 MAOB (0.67) MAOBIDO1AGXTMRGPRX4APP
SCHEMBL4242 0.79
SCHEMBL13722545 0.79 MAOB (0.61) MAOBIDO1AGXTMRGPRX4ABCB1
SCHEMBL919676 0.79 SMN1; SMN2 (0.50) MAOBACHE
SCHEMBL16710547 0.78 MAOB (0.71) MAOBIDO1AGXTMRGPRX4APP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110201649-A1 AGRICULTURAL COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-08-18 US disclosed
EP-2345328-A1 COMPOSITION FOR AGRICULTURAL USE Sumitomo Chemical Company, Limited (JP) 2011-07-20 EP disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS WIZ, TST, NAT1 MAOB 3730/4885IDO1 675/4885AGXT 21/4885
US-20110201649-A1 AGRICULTURAL COMPOSITION H1-0, H1-3, H1-2 MAOB 4351/4885IDO1 236/4885AGXT 48/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.