SCHEMBL921277

SCHEMBL921277

Fc1[c]ccc(OCc2cccc(F)c2)c1

nearest known ligand 0.59

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
MAOB P27338 16/20 0.59
MAOA P21397 3/20 0.55
NR4A2 P43354 2/20 0.54
PARP10 Q53GL7 1/20 0.50
IDO1 P14902 2/20 0.49
AGXT P21549 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL920621 0.85 ALOX5 (0.51) MAOBMAOANR4A2
SCHEMBL920432 0.85 ACHE (0.43) MAOBMAOANR4A2IDO1
SCHEMBL921872 0.85 MAOB (0.54) MAOBMAOANR4A2IDO1AGXT
SCHEMBL920443 0.85 MAOB (0.57) MAOBMAOAIDO1
SCHEMBL920733 0.84 MAOB (0.62) MAOBIDO1AGXT
SCHEMBL919898 0.82 MAOB (0.53) MAOBMAOANR4A2
SCHEMBL863891 0.82 MAOB (0.66) MAOBMAOANR4A2PARP10IDO1
SCHEMBL920508 0.81 FFAR1 (0.50) MAOBMAOA
SCHEMBL920402 0.78 MAPK1 (0.47) MAOA
SCHEMBL4426765 0.76 MAOB (0.67) MAOBMAOANR4A2PARP10IDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110201649-A1 AGRICULTURAL COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-08-18 US disclosed
EP-2345328-A1 COMPOSITION FOR AGRICULTURAL USE Sumitomo Chemical Company, Limited (JP) 2011-07-20 EP disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS WIZ, TST, NAT1 MAOB 3730/4885MAOA 3447/4885NR4A2 573/4885
US-20110201649-A1 AGRICULTURAL COMPOSITION H1-0, H1-3, H1-2 MAOB 4351/4885MAOA 4535/4885NR4A2 1956/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.