Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | KIF11 | P52732 | 1/20 | 0.31 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
| ▸ | NISCH | Q9Y2I1 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9685789 | 0.84 | SKP2 (0.41) | ALDH1A1HPGDCYP1A2SMN1; SMN2NISCH | |
| SCHEMBL5494452 | 0.83 | SKP2 (0.37) | KDM4EALDH1A1 | |
| SCHEMBL7765516 | 0.83 | RECQL (0.31) | — | |
| SCHEMBL8786524 | 0.80 | TDP1 (0.31) | — | |
| SCHEMBL9658554 | 0.80 | MAPT (0.41) | KDM4EALDH1A1HPGDCYP1A2SMN1; SMN2 | |
| SCHEMBL7756747 | 0.78 | — | — | |
| SCHEMBL8114298 | 0.76 | HRH1 (0.37) | CYP1A2 | |
| SCHEMBL9684915 | 0.73 | PARP1 (0.38) | ALDH1A1GAAHPGDPARP1 | |
| SCHEMBL8798735 | 0.72 | PDE3B (0.41) | KDM4EALDH1A1GAAMAPK10RIPK1 | |
| SCHEMBL9484797 | 0.71 | HPGD (0.43) | ALDH1A1GAAHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0430800-B1 | Substituted benzothiazolinones, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 1995-01-25 | — | — | EP | disclosed |
| US-5084469-A | Analgesics | ADIR ET COMPAGNIE (FR) | 1992-01-28 | — | — | US | disclosed |
| EP-0430800-A1 | Substituted benzothiazolinones, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1991-06-05 | — | — | EP | disclosed |