Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9204489 | 0.83 | KDM4E (0.34) | — | |
| SCHEMBL9685626 | 0.79 | MAOA (0.41) | — | |
| SCHEMBL9685789 | 0.78 | SKP2 (0.41) | — | |
| SCHEMBL8114298 | 0.76 | HRH1 (0.37) | — | |
| SCHEMBL7756732 | 0.72 | DRD2 (0.45) | — | |
| SCHEMBL5727378 | 0.70 | MAPT (0.39) | RECQL | |
| SCHEMBL7761424 | 0.70 | SIGMAR1 (0.46) | — | |
| SCHEMBL7756740 | 0.69 | CHRM2 (0.44) | — | |
| SCHEMBL9484797 | 0.68 | HPGD (0.43) | — | |
| SCHEMBL9483505 | 0.68 | PKM (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0841330-B1 | Aminomethyl heterocyclic derivatives, process of their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2001-06-27 | — | — | EP | claimed |
| CN-1182083-A | New heterocyclic aminomethyl compounds, process for preparing them and pharmaceutical compositions containing them | ADIR (FR) | 1998-05-20 | — | — | CN | claimed |
| EP-0841330-A1 | Aminomethyl heterocyclic derivatives, process of their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1998-05-13 | — | — | EP | claimed |
| CN-1072655-C | New heterocyclic aminomethyl compounds, process for preparing them and pharmaceutical compositions containing them | ADIR (FR) | 2001-10-10 | — | — | CN | disclosed |
| EP-0841330-B1 | Aminomethyl heterocyclic derivatives, process of their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2001-06-27 | — | — | EP | disclosed |
| US-5919784-A | ANXIETY, DEPRESSION | ADIR ET COMPAGNIE (FR) | 1999-07-06 | — | — | US | disclosed |
| CN-1182083-A | New heterocyclic aminomethyl compounds, process for preparing them and pharmaceutical compositions containing them | ADIR (FR) | 1998-05-20 | — | — | CN | disclosed |
| EP-0841330-A1 | Aminomethyl heterocyclic derivatives, process of their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1998-05-13 | — | — | EP | disclosed |